[(Ph₃Sn)₂(m-CDC)(CH₃OH)₂] | 1447448-13-6

• 英文名称: [(Ph₃Sn)₂(m-CDC)(CH₃OH)₂]
• CAS: 1447448-13-6
• 化学式: C₄₂H₄₈B₁₀O₆Sn₂
• 分子量: 994.37
• InChiKey: SZMJIQCQKYSBKI-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  甲醇 、 1,7-dicarba-closo-dodecarborane 、 三苯基氯化锡 在 三乙胺 作用下， 反应 48.0h， 以82%的产率得到[(Ph₃Sn)₂(m-CDC)(CH₃OH)₂]
  参考文献：
  名称：

  Syntheses, structural characterization and in vitro cytotoxic activity of triorganotin(IV) complexes based on 1,7-dihydroxycarbonyl-1,7-dicarba-closo-dodecaborane ligand

  摘要：

  Seven novel triorganotin(IV) compounds containing m-CDC2- (m-CDCH2 1,7-dihydroxycarbonyl-1,7-dicarba-closo-dodecaborane) have been synthesized and structural characterized. The central tin atoms are five-coordinated to assume a distorted trigonal bipyramidal configuration not only in the binuclear monomers 1, 3 and 4 but also in the polymers 2, 5, 6 and 7. It was observed that complexes 3, 4 and 5 could be obtained only in the presence of the ancillary carboxylate ligands, 2,3-pyrazinedicarboxylic acid, 2-pyridinecarboxylic acid and 2,6-pyridinedicarboxylic acid, respectively. The reaction of m-CDCH2 with (n-Bu3Sn)(2)O in the presence of the bridging ligands 4,4'-bipyridine and 4,4'-vinylenedipyridine afforded one-dimensional coordination polymers 6 and 7, respectively. Most of the complexes exhibit higher cytotoxic activities than cis-platin against two cancer cell lines, K-562 and Hela. (C) 2013 Elsevier B. V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2013.04.039