(Co(2-seleno-4-methylquinoline)2(H2O)2)PF6 | 1374525-78-6

• 英文名称: (Co(2-seleno-4-methylquinoline)2(H2O)2)PF6
• CAS: 1374525-78-6
• 化学式: C₂₀H₂₀CoN₂O₂Se₂*F₆P
• 分子量: 682.268
• InChiKey: QQMORDZERLVDMW-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  ammonium hexafluorophosphate 、 4-甲基喹啉-2-硫酮 、 cobalt(II) chloride hexahydrate 以 乙醇 为溶剂， 以56%的产率得到(Co(2-seleno-4-methylquinoline)2(H2O)2)PF6
  参考文献：
  名称：

  Synthesis, Characterization, DNA Binding, and Cleavage Activity of New Co(III) and Ru(II) Complexes of Substituted Quinolines

  摘要：

  The cobalt(III) and ruthenium(II) complexes of the type [M(L)(2)](n+) (M = Co(III) or Ru(II) ion, n = 3 for Co and 2 for Ru, L = 2-thiol/seleno 4-methylquinoline) were synthesized and structurally characterized. The spectral and magnetic data suggested octahedral geometry for all the complexes. DNA binding behaviors of these complexes with calf thymus DNA (CT-DNA) have been investigated by absorption spectra, viscosity, and thermal denaturation methods. The metal complexes intercalates into the DNA base stack. The oxidative cleavage activities of the complexes shows that the complexes act as potent nucleases.

  DOI：

  10.1080/15533174.2011.613439