| 247920-12-3

• CAS: 247920-12-3
• 化学式: C₁₉H₁₇AuClN₂*F₆P
• 分子量: 650.741
• InChiKey: IATQJOGFAAPBPV-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  在 sodium hexaflorophosphate 、 二氯甲烷 作用下， 以 乙腈 为溶剂， 以49%的产率得到金
  参考文献：
  名称：

  Electrochemical behaviour of cyclometallated gold(III) complexes. Evidence of transcyclometallation in the fate of electroreduced species

  摘要：

  The electrochemical behaviour of a series of neutral and cationic N-C and N-N-C cyclometallated gold(III) species: ([Au(py(1))(Cl)(2)], Hpy(1) = 2-benzylpyridine; [Au(bipy(n))(Cl)][PF6], Hbipy(1) = 6-benzyl-2,2'-bipyridine, Hbipy(2) = 6-(1-methylbenzyl)-2,2'-bipyridine, Hbipy(3) = 6-(1,1-dimethylbenzyl)-2,2'-bipyridine, Hbipy(4) = 6-phenyl-2,2'-bipyridine) has been investigated in different solvent systems using cyclic voltammetry and controlled-potential coulometry. All the species considered show, in cyclic voltammetry, an irreversible one-electron reduction in the potential range -0.9/-1.2 V versus Fc(+/0), using a Pt electrode. On the other hand, exhaustive coulometries have shown the consumption of a number of Faraday per mole within the range 1-2. The very complex decomposition of the electrogenerated species affords elemental gold and significant amounts of different gold by-products. In some situations (e.g. reduction of [Au(bipy(4))(Cl)][PF6]), working with 0.1 mol dm(-3) Na[PF6], CH3C solvent system, it has been possible to characterise the most abundant gold(III) compound, by NMR, FAB-MS, and elemental analysis. The analytical and spectroscopic data provide evidence for the N-C bis-cyclometallated gold(III) derivative (e.g. [Au(bipy(4))(2)][PF6]); the result entails quite an unusual transcyclometallation process. The same compound can also be obtained, albeit in very minor yield, by chemical reduction of [Au(bipy(4))(Cl)][PF6]. (C) 2001 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0022-328x(00)00822-6

文献信息

• Synthesis and Characterization of Mononuclear Amidogold( <scp>III</scp> ) Complexes − Crystal Structure of [Au(N ₂ C ₁₀ H ₇ (CMe ₂ C ₆ H ₄ )‐6](NHC ₆ H ₃ Me ₂ ‐2,6)][PF ₆ ] − Oxidation of 4‐Methylaniline to Azotoluene
  作者：Maria Agostina Cinellu、Giovanni Minghetti、Maria Vittoria Pinna、Sergio Stoccoro、Antonio Zucca、Mario Manassero

  DOI：10.1002/ejic.200200377

  日期：2003.6

  Mononuclear amidogold(III) complexes [Au(C,N,N)(NRR′)][PF 6 ] [C,N,N = N 2 C 10 H 7 (Cme 2 C 6 H 4 )-6, where N 2 C 10 H 8 = 2,2′-bipy; R = H, R′ = p -tolyl ( 5 ), o -xylyl ( 6 ), isobutyl ( 7 ), sec -butyl ( 8 ), R = R′ = Et ( 9 )], [Au(C,N)(AcO)(NHC 6 H 4 NO 2 -4)] ( 10 ) [C,N = NC 5 H 4 (CH 2 C 6 H 4 )-2, where NC 5 H 5 = py] and [Au(N,N)(NHC 6 H 4 NO 2 -4) 2 ][PF 6 ] ( 11 ) (N,N = 2,2′-bipy), have

  单核酰胺金 (III) 配合物 [Au(C,N,N)(NRR')][PF 6 ] [C,N,N = N 2 C 10 H 7 (Cme 2 C 6 H 4 )-6，其中 N 2 C 10 H 8 = 2,2'-bipy；R = H, R' = 对甲苯基 ( 5 ), 邻二甲苯基 ( 6 ), 异丁基 ( 7 ), 仲丁基 ( 8 ), R = R' = Et ( 9 )], [Au(C,N) )(AcO)(NHC 6 H 4 NO 2 -4)] ( 10 ) [C,N = NC 5 H 4 (CH 2 C 6 H 4 )-2，其中 NC 5 H 5 = py] 和 [Au( N,N)(NHC 6 H 4 NO 2 -4) 2 ][PF 6 ] ( 11 ) (N,N = 2,2'-bipy)，通过羟基、甲氧基的反应以相当好的产率合成, 或乙酰络合物 1−4 [Au(C,N,N)(OR)][PF
• Replacement of the chloride ligand in [Au(C,N,N)Cl][PF6] cyclometallated complexes by C, N, O and S donor anionic ligands
  作者：Maria Agostina Cinellu、Giovanni Minghetti、Maria Vittoria Pinna、Sergio Stoccoro、Antonio Zucca、Mario Manassero

  DOI：10.1039/a903925b

  日期：——

  Replacement of the chloride ligand in the cyclometallated complexes [Au(C,N,N)Cl][PF6] (C,N,N = N2C10H7(CH2C6H4)-6 1, N2C10H7(CHMeC6H4)-6 2, or N2C10H7(CMe2C6H4)-6 3, where N2C10H8 = 2,2′-bipy) by C, N, O and S donor anionic ligands Y was accomplished through different routes depending both on the nature of HY or the C,N,N ligand. Stable alkoxo [Au(C,N,N)(OR)][PF6] (R = Me or Et) and amido [Au(C,N,N)(NHAr)][PF6] (Ar = C6H4NO2-4) complexes were obtained in fairly good yields. The molecular structure of the thiolato complex [AuN2C10H7(CMe2C6H4)-6}(SPh)][PF6] has been determined by X-ray crystallography. The diorganogold(III) complex [Au(C,N,N)(C2Ph)][PF6] on addition of PPh3 (1∶2) undergoes reductive elimination to give [Au(PPh3)2][PF6] and an unsymmetric diarylacetylene.

  在环金属化复合物[Au(C,N,N)Cl][PF6]中，氯配体的替换通过不同的途径完成，具体取决于HY或C,N,N配体的性质，其中C,N,N = N2C10H7(CH2C6H4)-6 1、N2C10H7(CHMeC6H4)-6 2或N2C10H7(CMe2C6H4)-6 3，N2C10H8 = 2,2′-联吡啶。通过引入C、N、O和S供体阴离子配体Y，成功合成了稳定的烷氧基[Au(C,N,N)(OR)][PF6]（R = Me或Et）和酰胺[Au(C,N,N)(NHAr)][PF6]（Ar = C6H4NO2-4）配合物，产率相当不错。通过X射线晶体学确定了硫醇盐配合物[AuN2C10H7(CMe2C6H4)-6}(SPh)][PF6]的分子结构。在添加PPh3（1∶2）后，二烯基金(III)复合物[Au(C,N,N)(C2Ph)][PF6]经历还原消除，生成[Au(PPh3)2][PF6]和一种不对称的二芳基乙炔。
• New Variations on the Theme of Gold(III) C^∧N^∧N Cyclometalated Complexes as Anticancer Agents: Synthesis and Biological Characterization
  作者：Silvia Carboni、Antonio Zucca、Sergio Stoccoro、Laura Maiore、Massimiliano Arca、Fabrizio Ortu、Christian Artner、Bernhard K. Keppler、Samuel M. Meier-Menches、Angela Casini、Maria Agostina Cinellu

  DOI：10.1021/acs.inorgchem.8b02604

  日期：2018.12.3

  A series of novel (C∧N∧N) cyclometalated AuIII complexes of general formula [Au(bipydmb-H)X][PF6] (bipydmb-H = C∧N∧N cyclometalated 6-(1,1-dimethylbenzyl)-2,2′-bipyridine) were prepared with a range of anionic ligands X in the fourth coordination position, featuring C (alkynyl)-, N-, O-, or S-donor atoms. The X ligands are varied in nature and include three coumarins, 4-ethynylaniline, saccharine,

  一系列新颖的（C ∧ Ñ ∧ N）环金属化的Au III通式的配合物[AU（联吡啶DMB -H）X] [PF 6 ]（联吡啶DMB -H = C ∧ Ñ ∧ Ñ环金属6-（1,1- （-二甲基苄基）-2，2'-联吡啶）是在第四配位位置具有一系列阴离子配体X制备的，这些阴离子配体X具有C（炔基）-，N-，O-或S-给体原子。X配体在性质上是变化的，并且包括三种香豆素，4-乙炔基苯胺，糖精和硫代-β - d-葡萄糖四乙酸酯，三肽谷胱甘肽（GSH）和衍生自4-乙炔基苯胺的香豆素取代的酰胺。金（I）络合物[Au（C 2 ArNHCOQ）（PPh 3）]（HC 2 ArNHCOQ = N-（4-乙炔基苯基）-2-oxo-2 H-色烯-3-羧酰胺）也用于比较。这些新化合物通过包括NMR，吸收和发射光谱在内的分析技术进行了全面表征。通过单晶X射线衍射解析了三种环金属化的Au III配合物和Au I衍生物的晶体结构。在体外评估了新的Au