1-[(2,2,3,3,4,4,5,5,6,6-decafluoropiperidin-1-yl)-difluoromethyl]-2,2,3,3,4,4,5,5,6,6-decafluoropiperidine | 133333-42-3

• 英文名称: 1-[(2,2,3,3,4,4,5,5,6,6-decafluoropiperidin-1-yl)-difluoromethyl]-2,2,3,3,4,4,5,5,6,6-decafluoropiperidine
• CAS: 133333-42-3
• 化学式: C₁₁F₂₂N₂
• 分子量: 578.099
• InChiKey: DFELWHICQMKBLJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.35
• 重原子数：
  35.0
• 可旋转键数：
  2.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  6.48
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为产物：
  描述：

  二哌啶甲烷 在 氢氟酸 作用下， 以0.1%的产率得到1-[(2,2,3,3,4,4,5,5,6,6-decafluoropiperidin-1-yl)-difluoromethyl]-2,2,3,3,4,4,5,5,6,6-decafluoropiperidine
  参考文献：
  名称：

  On the electrochemical fluorination of derivatives of morpholine and piperidine

  摘要：

  Electrochemical fluorination (ECF) of alpha,omega-dimorpholino- and dipiperidino-alkanes of different chain length (n = 1-6) and of morpholinocyclohexene gave the perfluoro derivatives in yields up to 45%. By ring contractions, fragmentations and rearrangements several side products were obtained. Conclusions on the mechanism of ECF, based on a sterical model, were drawn.

  DOI：

  10.1016/s0022-1139(00)80306-1