10-(2-(allyloxy)-5-methoxyphenyl)-3,7-bis(diethylcarbamoyl)-5,5-difluoro-5H-5l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium | 1028570-01-5

• 英文名称: 10-(2-(allyloxy)-5-methoxyphenyl)-3,7-bis(diethylcarbamoyl)-5,5-difluoro-5H-5l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium
• CAS: 1028570-01-5
• 化学式: C₂₉H₃₅BF₂N₄O₄
• 分子量: 552.429
• InChiKey: XNEIMYKCSURYON-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  10-(2-(allyloxy)-5-methoxyphenyl)-3,7-bis(diethylcarbamoyl)-5,5-difluoro-5H-5l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium 在 四(三苯基膦)钯 作用下， 以 乙醇 为溶剂， 反应 6.0h， 以70%的产率得到HKOCl-1
  参考文献：
  名称：

  A Highly Specific BODIPY-Based Fluorescent Probe for the Detection of Hypochlorous Acid

  摘要：

  A fluorescent probe, HKOCl-1, has been successfully developed for the detection of hypochlorous acid on the basis of a specific reaction with p-methoxyphenol. The formation of HOCl has been successfully detected not only in an abiotic system but also in an enzymatic system (myeloperoxidase/H(2)O(2)/Cl(-) system) and in living macrophage cells upon stimulation. This new probe might be used as an efficient tool for probing the roles HOCl plays in biological systems.

  DOI：

  10.1021/ol800507m
• 作为产物：
  描述：

  5-[[5-(diethylcarbamoyl)-1H-pyrrol-2-yl]-(5-methoxy-2-prop-2-enoxyphenyl)methylidene]-N,N-diethylpyrrole-2-carboxamide 在 三氟化硼乙醚 、 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 4.0h， 以61%的产率得到10-(2-(allyloxy)-5-methoxyphenyl)-3,7-bis(diethylcarbamoyl)-5,5-difluoro-5H-5l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium
  参考文献：
  名称：

  A Highly Specific BODIPY-Based Fluorescent Probe for the Detection of Hypochlorous Acid

  摘要：

  A fluorescent probe, HKOCl-1, has been successfully developed for the detection of hypochlorous acid on the basis of a specific reaction with p-methoxyphenol. The formation of HOCl has been successfully detected not only in an abiotic system but also in an enzymatic system (myeloperoxidase/H(2)O(2)/Cl(-) system) and in living macrophage cells upon stimulation. This new probe might be used as an efficient tool for probing the roles HOCl plays in biological systems.

  DOI：

  10.1021/ol800507m

文献信息

• WO2008/110063
  申请人：——

  公开号：——

  公开（公告）日：——