2-(tert-butylsulphanyl)-2-ferrocenyl-1-(4-methylphenyl)-1-ethanol | 401513-14-2

• 英文名称: 2-(tert-butylsulphanyl)-2-ferrocenyl-1-(4-methylphenyl)-1-ethanol
• CAS: 401513-14-2
• 化学式: C₂₃H₂₈FeOS
• 分子量: 408.388
• InChiKey: TTXNMKDLFVDPEY-LWPKXAGOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  tert-butyl[(ferrocenyl)(trimethylsilyl)methyl]sulphide 、 对甲基苯甲醛 在 cesium fluoride 作用下， 以 乙腈 为溶剂， 以52%的产率得到2-(tert-butylsulphanyl)-2-ferrocenyl-1-(4-methylphenyl)-1-ethanol
  参考文献：
  名称：

  Synthesis and reactivity of achiral and of a novel planar chiral thioferrocenoylsilanes

  摘要：

  The reactions of thioferrocenoylsilanes with organolithium reagents, dienes and reducing agents which afford alpha -silyl sulphides, dihydrothiopyranes and alpha -silyl ferrocenyl thiols, respectively, have been investigated. alpha -Silyl sulphides were further functionalised through carbodesilylation with aldehydes. We also report the synthesis of a new planar chiral thioferrocencylsilane that gave good diastereomeric excess in the reaction with t-butyllithium, lithium lutidine and 2,3-dimethylbuta-1,3-diene. The 1,1'-bis-thioferrocenoylsilane, too unstable to be isolated, was trapped in situ with dienes. (C) 2001 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0022-328x(01)00944-5