1-(n-pentyl)-1,2-dicarba-closo-dodecaborane | 75482-33-6

• 英文名称: 1-(n-pentyl)-1,2-dicarba-closo-dodecaborane
• 英文别名: 1-(n-amyl)-ortho-closocarborane-12；1-pentyl-o-carborane
• CAS: 75482-33-6
• 化学式: C₇H₂₂B₁₀
• 分子量: 214.362
• InChiKey: KOCWBBRSIIETJR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
  None
• 氢给体数：
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• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  在 丁烷 作用下， 以 neat (no solvent) 为溶剂， 生成 1-(2-methylbutyl)-o-carborane 、 1-(n-pentyl)-1,2-dicarba-closo-dodecaborane
  参考文献：
  名称：

  o-Carboranylcarbene and m-carboranylcarbene

  摘要：

  DOI：

  10.1021/ja00375a033

文献信息

• Directive effects in the hydroboration of 1-alkenyl derivatives of o-carborane with representative hydroborating agents
  作者：G.W. Kabalka、G. Hondrogiannis

  DOI：10.1016/s0022-328x(96)06695-8

  日期：1997.5

  A series of 1-alkenyl-o-carboranes was hydroborated using representative hydroborating agents with different steric requirements. The steric and electronic effects of the carboranyl group were evaluated by examining the distribution of the isomeric alcohols obtained after oxidation of the intermediate carboranyl-substituted organoboranes.

  一系列的1-链烯基- ö -carboranes使用代表hydroborating剂具有不同的空间要求是硼氢化。通过检查在中间体碳硼烷基取代的有机硼烷的氧化后获得的异构醇的分布，评估了碳硼烷基的空间和电子效应。
• Nickel-catalyzed cross-coupling of sterically hindered 1-bromomethyl-o-carborane with alkyl and aryl Grignard reagents
  作者：Juyou Lu、Hong Wan、Yunna Xue、Yongmei Du、Jian Lu

  DOI：10.1016/j.tet.2015.08.022

  日期：2015.10

  A convenient and efficient Ni-catalyzed reaction has been developed for synthesis of mono-substituted o-carboranes, involving cross-coupling of readily available and sterically hindered 1-bromomethyl-o-carborane with various alkyl and aryl Grignard reagents under mild conditions, and the corresponding o-carborane derivatives were obtained in good to excellent yields. This method should provide a new

  一种方便和有效的Ni基催化的反应已被开发用于合成单取代ø -carboranes，涉及容易获得的交叉耦合和空间位阻的1-溴甲基- ö -carborane与各种烷基和芳基在温和条件下的格氏试剂，和相应Ó -carborane衍生物在良好，获得优良的产率。这种方法应提供建设药物化学和材料化学多样的和有用的官能化硼簇化合物的新策略。
• Orlov, V. M.; Pustobaev, V. N.; Poroshina, T. Yu., Doklady Physical Chemistry
  作者：Orlov, V. M.、Pustobaev, V. N.、Poroshina, T. Yu.、Ol'shevskaya, V. A.、Zakharkin, L. I.、Gal'chenko, G. L.

  DOI：——

  日期：——