| 220716-25-6

• CAS: 220716-25-6
• 化学式: C₈H₈AuBr₂NOS
• 分子量: 522.998
• InChiKey: WBLCHFYNUNKYDW-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  <2>-Pyridylmercaptoaceton 在 Na₂CO₃ 作用下， 以 丙酮 为溶剂， 生成
  参考文献：
  名称：

  Multidonor Ligands. 2.¹ Room-Temperature C(sp³)−H Activation of 2-(Alkylthio)pyridine by Gold(III) Complexes

  摘要：

  Na[AuCl4] reacts with [py{SCH2C(O)R}-2] (py-2 = 2-pyridyl) at room temperature to give cyclometalated alkylgold(III) complexes [AuCl2{py{SCHC(O)R}-2}] [R = Ph (1a); Me (1b), OMe (1b)], which in turn react with NaBr or with PR'(3) in the presence of NaClO4 to give [AuBr2{py{SCHC(O)R}-2}] [R = Ph (2a), Me (2b)] or a mixture of SP4-3- and SP4-4-[AuCl-{py{SCHC(O)R}-2}(PPh3)]ClO4 [R = Ph (3a), Me (3b)]. This mixture of isomers converted to the isomer SP4-4 upon refluxing in chloroform. When the last reaction was made using P(C6H4OMe-4)(3), the main products were [AuCl{P(C6H4OMe-4)(3)}] and [Hpy{SCH2C(O)Ph}2]ClO4. The crystal structure of the latter has been determined.

  DOI：

  10.1021/om980747m