[(Bu2Sn(6-nitropiperonylate))2O]2*CHCl3 | 1210038-92-8

• 英文名称: [(Bu2Sn(6-nitropiperonylate))2O]2*CHCl3
• CAS: 1210038-92-8
• 化学式: CHCl₃*C₆₄H₈₈N₄O₂₆Sn₄
• 分子量: 1923.63
• InChiKey: JNUXBINTAKRBFI-UHFFFAOYSA-J

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  氯仿 、 6-硝基-1,3-苯并二氧代-5-羧酸 、 二正丁基氧化锡 以 甲苯 为溶剂， 以65%的产率得到[(Bu2Sn(6-nitropiperonylate))2O]2*CHCl3
  参考文献：
  名称：

  In vitro biological studies and structural elucidation of organotin(IV) derivatives of 6-nitropiperonylic acid: Crystal structure of {[(CH2O2C6H2(o-NO2)COO)SnBu2]2O}2

  摘要：

  Six organotin(IV) compounds with general formulae R3SnL, R = Me (2), Ph (6), R2SnL2, R = Me (1), Et (3), n-Oct (5), [((R2SnL)(2)O)(2)], R = Bu (4). L = 6-nitropiperonylate, have been prepared. The newly synthesized compounds have been characterized by elemental analysis, FT-IR and multinuclear NMR (H-1, C-13 and Sn-119). The structure of 4 has been determined by single crystal X-ray crystallography which is triclinic with the space group P (1) over bar The crystal Structure contains centrosymmetric dimer distannoxane with planar central four-membered Sn2O2 core. The 6-nitropiperonylate ligand shows different modes of coordination with Sn, as a result the central Sn2O2 core is fused with two four-membered (Sn(1)-O(1)-Sn(2)-O(13)) and two six-membered (Sn(1)-O(13)-Sn(2)-O(8)-C(9)-O(7)) rings. The endocyclic Sn(2) is six coordinated in a skew trapezoidal bipyramidal environment while exocyclic Sn(1) is five coordinated with distorted trigonal bipyramidal geometry. The ligand acid and synthesized organotin compounds were also screened for antibacterial, antifungal, brine-shrimp lethality and potato disc antitumor activities. Results of bioassay demonstrate that organotin derivatives are in general more active than the ligand acid. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2009.07.039