cis-4-(1-Methylethenyl)-1-methylbicyclo<4.1.0>heptane | 62740-28-7

• 英文名称: cis-4-(1-Methylethenyl)-1-methylbicyclo<4.1.0>heptane
• 英文别名: cis-4-(1-Methylethenyl)-1-methylbicyclo[4.1.0]heptane
• CAS: 62740-28-7
• 化学式: C₁₁H₁₈
• 分子量: 150.264
• InChiKey: FCEDWXCHSROGJG-KHUXNXPUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.39
• 重原子数：
  11.0
• 可旋转键数：
  1.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  0.0

反应信息

• 作为产物：
  描述：

  二碘甲烷 、 limonene. 在 乙酰氯 、 copper(l) chloride 、 锌 作用下， 以 乙醚 为溶剂， 生成 1-methyl-4-(1-methylcyclopropyl)-1-cyclohexene 、 1-methyl-4-(1-methylcyclopropyl)bicyclo<4.1.0>heptane 、 cis-4-(1-Methylethenyl)-1-methylbicyclo<4.1.0>heptane 、 trans-4-(1-Methylethenyl)-1-methylbicyclo<4.1.0>heptane
  参考文献：
  名称：

  Regioselectivity and solvent effects in cyclopropanation of alkadienes

  摘要：

  A comparison of the regioselectivities for monocyclopropanation of limonene and 4-vinylclohexene using diiodomethane with zinc dust and copper(I) chloride in ether, with diethylzinc in toluene, or with triethylaluminum in toluene-dichloromethane has been carried out. Some studies were also done using dibromomethane with zinc dust and copper(I) chloride in ether. The procedure using diethylzinc in toluene exhibited the least steric hindrance toward cyclopropanation at more highly substituted, electron-rich double bonds. In a study of solvent effects on the diiodomethane, zinc dust, and copper(I) chloride procedure, use of diisopropyl ether as a reaction solvent proved to be a satisfactory method for almost doubling the steric requirements of the cyclopropanating reagent.

  DOI：

  10.1021/jo00006a044