N-(2-(二乙胺基)乙基)-4-碘苯酰胺 | 9012-49-1

• 分子结构分类: 转移酶 - 转移一碳基团 - 羧基和氨基甲酰基转移酶
• 中文名称: N-(2-(二乙胺基)乙基)-4-碘苯酰胺
• 英文名称: aspartate carbamoyltransferase
• 英文别名: carbamylaspartotranskinase；aspartate transcarbamylase；aspartate carbamyltransferase；aspartic acid transcarbamoylase；aspartic carbamyltransferase；aspartic transcarbamylase；L-aspartate transcarbamoylase；L-aspartate transcarbamylase；carbamoylaspartotranskinase；aspartate transcarbamoylase；ATCase；α-amylase
• CAS: 9012-49-1

反应信息

• 作为试剂：
  描述：

  6^A-(N-dansyl-L-cysteine)-6^H-tosyl-γ-cyclodextrin 在 calcium chloride 、 N-(2-(二乙胺基)乙基)-4-碘苯酰胺 作用下， 以 acetate buffer 为溶剂， 反应 72.0h， 以52%的产率得到
  参考文献：
  名称：

  Hetero-bifunctional γ-cyclodextrins having dansylcysteine and tosyl groups at two adjacent sugar units: synthesis and determination of regio-chemistry

  摘要：

  Ditosylation of two adjacent 6-positions of gamma-cyclodextrin, subsequent mono-substitution with L-cysteine and final condensation with dansyl chloride afford the title compounds whose clockwise and counterclockwise isomers are separated from each other and their regio-chemistry is unambiguously determined by a new strategy based on the combination of enzyme degradation of the hetero-bifunctional gamma-cyclodextrin to the corresponding disubstituted maltotriose and fragmentation analysis of the latter by PSD-MS technique. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2007.03.003