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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 噻吩并嘧啶酮衍生物

    噻吩并嘧啶酮衍生物

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 5,6-dimethyl-2-[(1S)-1-[[5-morpholin-4-yl-4-[[(2S)-oxolan-2-yl]methyl]-1,2,4-triazol-3-yl]sulfanyl]ethyl]-3H-thieno[2,3-d]pyrimidin-4-one —— C21H28N6O3S2
    5,6-dimethyl-2-[(1S)-1-[[5-morpholin-4-yl-4-[[(2S)-oxolan-2-yl]methyl]-1,2,4-triazol-3-yl]sulfanyl]ethyl]-3H-thieno[2,3-d]pyrimidin-4-one
    —— 1-[(3S,5S)-3,5-dimethylpiperidin-1-yl]-2-(5-phenylthieno[2,3-d]pyrimidin-4-yl)sulfanylethanone —— C21H23N3OS2
    1-[(3S,5S)-3,5-dimethylpiperidin-1-yl]-2-(5-phenylthieno[2,3-d]pyrimidin-4-yl)sulfanylethanone
    —— (2R)-N-(2-methylphenyl)-2-[(12-oxo-11-propyl-7-thia-9,11-diazatricyclo[6.4.0.02,6]dodeca-1(8),2(6),9-trien-10-yl)sulfanyl]propanamide —— C22H25N3O2S2
    (2R)-N-(2-methylphenyl)-2-[(12-oxo-11-propyl-7-thia-9,11-diazatricyclo[6.4.0.02,6]dodeca-1(8),2(6),9-trien-10-yl)sulfanyl]propanamide
    —— N-[(1S)-2-methyl-1-thiophen-2-ylpropyl]-2-(4-oxo-5-phenylthieno[2,3-d]pyrimidin-3-yl)acetamide —— C22H21N3O2S2
    N-[(1S)-2-methyl-1-thiophen-2-ylpropyl]-2-(4-oxo-5-phenylthieno[2,3-d]pyrimidin-3-yl)acetamide
    —— 10-[(2S)-1-[(3S,5S)-3,5-dimethylpiperidin-1-yl]-1-oxopropan-2-yl]sulfanyl-11-propyl-7-thia-9,11-diazatricyclo[6.4.0.02,6]dodeca-1(8),2(6),9-trien-12-one —— C22H31N3O2S2
    10-[(2S)-1-[(3S,5S)-3,5-dimethylpiperidin-1-yl]-1-oxopropan-2-yl]sulfanyl-11-propyl-7-thia-9,11-diazatricyclo[6.4.0.02,6]dodeca-1(8),2(6),9-trien-12-one
    —— [2-(ethylamino)-2-oxoethyl] 4-methyl-2-oxo-6-thia-1,8-diazatricyclo[7.5.0.03,7]tetradeca-3(7),4,8-triene-5-carboxylate —— C17H21N3O4S
    [2-(ethylamino)-2-oxoethyl] 4-methyl-2-oxo-6-thia-1,8-diazatricyclo[7.5.0.03,7]tetradeca-3(7),4,8-triene-5-carboxylate
    —— (2R)-N-[(3R)-1,1-dioxothiolan-3-yl]-N-ethyl-2-[(4-oxo-3-prop-2-enyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)sulfanyl]propanamide —— C22H29N3O4S3
    (2R)-N-[(3R)-1,1-dioxothiolan-3-yl]-N-ethyl-2-[(4-oxo-3-prop-2-enyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)sulfanyl]propanamide
    —— (2R)-N-cyclohexyl-2-(5,6-dimethyl-4-oxo-3-prop-2-enylthieno[2,3-d]pyrimidin-2-yl)sulfanyl-N-methylpropanamide —— C21H29N3O2S2
    (2R)-N-cyclohexyl-2-(5,6-dimethyl-4-oxo-3-prop-2-enylthieno[2,3-d]pyrimidin-2-yl)sulfanyl-N-methylpropanamide
    —— (2R)-N-[(3S)-1,1-dioxothiolan-3-yl]-N-methyl-2-[(4-oxo-3-prop-2-enyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)sulfanyl]propanamide —— C21H27N3O4S3
    (2R)-N-[(3S)-1,1-dioxothiolan-3-yl]-N-methyl-2-[(4-oxo-3-prop-2-enyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)sulfanyl]propanamide
    —— 2-[2-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-2-oxoethyl]sulfanyl-3-(3-ethoxypropyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-one —— C21H31N3O4S2
    2-[2-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-2-oxoethyl]sulfanyl-3-(3-ethoxypropyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-one
    —— (7R)-2-[(1S)-1-[[5-[(4-fluorophenoxy)methyl]-1,3,4-oxadiazol-2-yl]sulfanyl]ethyl]-7-methyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C22H21FN4O3S2
    (7R)-2-[(1S)-1-[[5-[(4-fluorophenoxy)methyl]-1,3,4-oxadiazol-2-yl]sulfanyl]ethyl]-7-methyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (2S)-N-[(4-fluorophenyl)methyl]-2-[(4-oxo-3-prop-2-enyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)sulfanyl]propanamide —— C23H24FN3O2S2
    (2S)-N-[(4-fluorophenyl)methyl]-2-[(4-oxo-3-prop-2-enyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)sulfanyl]propanamide
    —— (2R)-N-cyclohexyl-2-[(3-ethyl-4-oxo-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)sulfanyl]-N-methylpropanamide —— C22H31N3O2S2
    (2R)-N-cyclohexyl-2-[(3-ethyl-4-oxo-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)sulfanyl]-N-methylpropanamide
    —— (2S)-N-cyclohexyl-2-[(3-ethyl-4-oxo-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)sulfanyl]-N-methylpropanamide —— C22H31N3O2S2
    (2S)-N-cyclohexyl-2-[(3-ethyl-4-oxo-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)sulfanyl]-N-methylpropanamide
    —— 2-[(1S)-1-(3-chloropyridin-2-yl)sulfanylethyl]-5-(furan-2-yl)-3H-thieno[2,3-d]pyrimidin-4-one —— C17H12ClN3O2S2
    2-[(1S)-1-(3-chloropyridin-2-yl)sulfanylethyl]-5-(furan-2-yl)-3H-thieno[2,3-d]pyrimidin-4-one
    —— (2S)-2-[(3-ethyl-4-oxo-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)sulfanyl]-N-(4-methylphenyl)propanamide —— C22H25N3O2S2
    (2S)-2-[(3-ethyl-4-oxo-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)sulfanyl]-N-(4-methylphenyl)propanamide
    —— N-[(3R)-1,1-dioxothiolan-3-yl]-2-[[(7S)-7-methyl-4-oxo-3-prop-2-enyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl]sulfanyl]acetamide —— C20H25N3O4S3
    N-[(3R)-1,1-dioxothiolan-3-yl]-2-[[(7S)-7-methyl-4-oxo-3-prop-2-enyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl]sulfanyl]acetamide
    —— N-[(1S)-1-(2-chlorophenyl)ethyl]-2-[3-(3-ethoxypropyl)-5,6-dimethyl-4-oxothieno[2,3-d]pyrimidin-2-yl]sulfanylacetamide —— C23H28ClN3O3S2
    N-[(1S)-1-(2-chlorophenyl)ethyl]-2-[3-(3-ethoxypropyl)-5,6-dimethyl-4-oxothieno[2,3-d]pyrimidin-2-yl]sulfanylacetamide
    —— N-[(3S)-1,1-dioxothiolan-3-yl]-2-[[(7S)-7-methyl-4-oxo-3-prop-2-enyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl]sulfanyl]acetamide —— C20H25N3O4S3
    N-[(3S)-1,1-dioxothiolan-3-yl]-2-[[(7S)-7-methyl-4-oxo-3-prop-2-enyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl]sulfanyl]acetamide
    —— (2S)-2-[[3-(2-fluorophenyl)-4-oxo-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl]sulfanyl]-N-(3-methyl-1,2-oxazol-5-yl)propanamide —— C23H21FN4O3S2
    (2S)-2-[[3-(2-fluorophenyl)-4-oxo-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl]sulfanyl]-N-(3-methyl-1,2-oxazol-5-yl)propanamide
    —— 2-[[(7S)-7-methyl-4-oxo-3-prop-2-enyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl]sulfanyl]-N-[(1R)-1-thiophen-2-ylethyl]acetamide —— C22H25N3O2S3
    2-[[(7S)-7-methyl-4-oxo-3-prop-2-enyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl]sulfanyl]-N-[(1R)-1-thiophen-2-ylethyl]acetamide
    —— (2S)-2-(3-cyclopentyl-5,6-dimethyl-4-oxothieno[2,3-d]pyrimidin-2-yl)sulfanyl-N-pyrimidin-2-ylpropanamide —— C20H23N5O2S2
    (2S)-2-(3-cyclopentyl-5,6-dimethyl-4-oxothieno[2,3-d]pyrimidin-2-yl)sulfanyl-N-pyrimidin-2-ylpropanamide
    —— (7S)-7-methyl-2-[(1R)-1-[1-(2-thiophen-2-ylethyl)tetrazol-5-yl]sulfanylethyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C20H22N6OS3
    (7S)-7-methyl-2-[(1R)-1-[1-(2-thiophen-2-ylethyl)tetrazol-5-yl]sulfanylethyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— (7S)-2-[(1S)-1-[[5-(4-methoxyanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]ethyl]-7-methyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C22H23N5O2S3
    (7S)-2-[(1S)-1-[[5-(4-methoxyanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]ethyl]-7-methyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— 5,6-dimethyl-2-[2-[(2R)-2-methylmorpholin-4-yl]-2-oxoethyl]sulfanyl-3-propan-2-ylthieno[2,3-d]pyrimidin-4-one —— C18H25N3O3S2
    5,6-dimethyl-2-[2-[(2R)-2-methylmorpholin-4-yl]-2-oxoethyl]sulfanyl-3-propan-2-ylthieno[2,3-d]pyrimidin-4-one
    —— N-[(2S)-2-cyano-3-methylbutan-2-yl]-2-[5-(3,4-dimethylphenyl)-3-methyl-4-oxothieno[2,3-d]pyrimidin-2-yl]sulfanylacetamide —— C23H26N4O2S2
    N-[(2S)-2-cyano-3-methylbutan-2-yl]-2-[5-(3,4-dimethylphenyl)-3-methyl-4-oxothieno[2,3-d]pyrimidin-2-yl]sulfanylacetamide
    —— 2-[2-[(2R)-2-methylpiperidin-1-yl]-2-oxoethyl]sulfanyl-6-phenyl-3-prop-2-enylthieno[2,3-d]pyrimidin-4-one —— C23H25N3O2S2
    2-[2-[(2R)-2-methylpiperidin-1-yl]-2-oxoethyl]sulfanyl-6-phenyl-3-prop-2-enylthieno[2,3-d]pyrimidin-4-one
    —— (2R)-N-[(2S)-2-cyano-3-methylbutan-2-yl]-2-[5-(3,4-dimethylphenyl)-3-methyl-4-oxothieno[2,3-d]pyrimidin-2-yl]sulfanylpropanamide —— C24H28N4O2S2
    (2R)-N-[(2S)-2-cyano-3-methylbutan-2-yl]-2-[5-(3,4-dimethylphenyl)-3-methyl-4-oxothieno[2,3-d]pyrimidin-2-yl]sulfanylpropanamide
    —— (2R)-N-cyclopentyl-2-[5-(3,4-dimethylphenyl)-3-methyl-4-oxothieno[2,3-d]pyrimidin-2-yl]sulfanylpropanamide —— C23H27N3O2S2
    (2R)-N-cyclopentyl-2-[5-(3,4-dimethylphenyl)-3-methyl-4-oxothieno[2,3-d]pyrimidin-2-yl]sulfanylpropanamide
    —— 5-(3,4-dimethylphenyl)-3-methyl-2-[(2R)-1-oxo-1-pyrrolidin-1-ylpropan-2-yl]sulfanylthieno[2,3-d]pyrimidin-4-one —— C22H25N3O2S2
    5-(3,4-dimethylphenyl)-3-methyl-2-[(2R)-1-oxo-1-pyrrolidin-1-ylpropan-2-yl]sulfanylthieno[2,3-d]pyrimidin-4-one
    —— 3-(3-methylphenyl)-2-{[(2E)-3-phenylprop-2-en-1-yl]sulfanyl}-6-(propan-2-yl)-3,5,6,8-tetrahydro-4H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-one —— C28H28N2O2S2
    3-(3-methylphenyl)-2-{[(2E)-3-phenylprop-2-en-1-yl]sulfanyl}-6-(propan-2-yl)-3,5,6,8-tetrahydro-4H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-one
    —— (2S)-2-[5-(3,4-dimethylphenyl)-3-methyl-4-oxothieno[2,3-d]pyrimidin-2-yl]sulfanyl-N-(2-methylphenyl)propanamide —— C25H25N3O2S2
    (2S)-2-[5-(3,4-dimethylphenyl)-3-methyl-4-oxothieno[2,3-d]pyrimidin-2-yl]sulfanyl-N-(2-methylphenyl)propanamide
    —— (2R)-2-[[5-(4-fluorophenyl)-4-oxo-3H-thieno[2,3-d]pyrimidin-2-yl]sulfanyl]-N-(3-methyl-1,2-oxazol-5-yl)propanamide —— C19H15FN4O3S2
    (2R)-2-[[5-(4-fluorophenyl)-4-oxo-3H-thieno[2,3-d]pyrimidin-2-yl]sulfanyl]-N-(3-methyl-1,2-oxazol-5-yl)propanamide
    —— (2R)-N-[(2R)-2-cyano-3-methylbutan-2-yl]-2-[5-(3,4-dimethylphenyl)-3-methyl-4-oxothieno[2,3-d]pyrimidin-2-yl]sulfanylpropanamide —— C24H28N4O2S2
    (2R)-N-[(2R)-2-cyano-3-methylbutan-2-yl]-2-[5-(3,4-dimethylphenyl)-3-methyl-4-oxothieno[2,3-d]pyrimidin-2-yl]sulfanylpropanamide
    —— 2-[(1R)-1-[(4-cyclopropyl-5-indol-3-ylidene-1H-1,2,4-triazol-3-yl)sulfanyl]ethyl]-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine —— C23H23N7S2
    2-[(1R)-1-[(4-cyclopropyl-5-indol-3-ylidene-1H-1,2,4-triazol-3-yl)sulfanyl]ethyl]-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine
    —— 6-[[(7S)-3-(2-fluorophenyl)-7-methyl-4-oxo-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl]sulfanylmethyl]-1,3-dimethylpyrimidine-2,4-dione —— C24H23FN4O3S2
    6-[[(7S)-3-(2-fluorophenyl)-7-methyl-4-oxo-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl]sulfanylmethyl]-1,3-dimethylpyrimidine-2,4-dione
    —— 3-methyl-2-[(2R)-1-(4-methylpiperidin-1-yl)-1-oxopropan-2-yl]sulfanyl-5-phenylthieno[2,3-d]pyrimidin-4-one —— C22H25N3O2S2
    3-methyl-2-[(2R)-1-(4-methylpiperidin-1-yl)-1-oxopropan-2-yl]sulfanyl-5-phenylthieno[2,3-d]pyrimidin-4-one
    —— (2R)-N-(1-adamantyl)-2-(3-methyl-4-oxo-5-phenylthieno[2,3-d]pyrimidin-2-yl)sulfanylpropanamide —— C26H29N3O2S2
    (2R)-N-(1-adamantyl)-2-(3-methyl-4-oxo-5-phenylthieno[2,3-d]pyrimidin-2-yl)sulfanylpropanamide
    —— 3-[3-[(3S)-3-(1H-benzimidazol-2-yl)piperidin-1-yl]-3-oxopropyl]thieno[2,3-d]pyrimidin-4-one —— C21H21N5O2S
    3-[3-[(3S)-3-(1H-benzimidazol-2-yl)piperidin-1-yl]-3-oxopropyl]thieno[2,3-d]pyrimidin-4-one
    —— N-[(S)-(4-fluorophenyl)-thiophen-2-ylmethyl]-2-(4-oxo-3-prop-2-enylthieno[2,3-d]pyrimidin-2-yl)sulfanylacetamide —— C22H18FN3O2S3
    N-[(S)-(4-fluorophenyl)-thiophen-2-ylmethyl]-2-(4-oxo-3-prop-2-enylthieno[2,3-d]pyrimidin-2-yl)sulfanylacetamide
    —— (7S)-3-[[3-(4-methoxyphenyl)-1,2-oxazol-5-yl]methyl]-7-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-one —— C22H21N3O3S
    (7S)-3-[[3-(4-methoxyphenyl)-1,2-oxazol-5-yl]methyl]-7-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-one
    —— 11-[2-(Benzenesulfonyl)ethyl]-7-thia-9,11-diazatricyclo[6.4.0.02,6]dodeca-1(8),2(6),9-trien-12-one —— C17H16N2O3S2
    11-[2-(Benzenesulfonyl)ethyl]-7-thia-9,11-diazatricyclo[6.4.0.02,6]dodeca-1(8),2(6),9-trien-12-one
    —— (2R)-N-cyclohexyl-N-methyl-2-(4-oxo-3-phenylthieno[2,3-d]pyrimidin-2-yl)sulfanylpropanamide —— C22H25N3O2S2
    (2R)-N-cyclohexyl-N-methyl-2-(4-oxo-3-phenylthieno[2,3-d]pyrimidin-2-yl)sulfanylpropanamide
    —— (2R)-N-[(4-fluorophenyl)methyl]-2-(4-oxo-3-prop-2-enylthieno[2,3-d]pyrimidin-2-yl)sulfanylpropanamide —— C19H18FN3O2S2
    (2R)-N-[(4-fluorophenyl)methyl]-2-(4-oxo-3-prop-2-enylthieno[2,3-d]pyrimidin-2-yl)sulfanylpropanamide
    —— 2-[2-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-2-oxoethyl]sulfanyl-3-prop-2-enylthieno[2,3-d]pyrimidin-4-one —— C17H21N3O3S2
    2-[2-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-2-oxoethyl]sulfanyl-3-prop-2-enylthieno[2,3-d]pyrimidin-4-one
    —— (2S)-N-(1-adamantyl)-2-(4-oxo-3-phenylthieno[2,3-d]pyrimidin-2-yl)sulfanylpropanamide —— C25H27N3O2S2
    (2S)-N-(1-adamantyl)-2-(4-oxo-3-phenylthieno[2,3-d]pyrimidin-2-yl)sulfanylpropanamide
    —— (2S)-N-cyclohexyl-N-methyl-2-(4-oxo-3-phenylthieno[2,3-d]pyrimidin-2-yl)sulfanylpropanamide —— C22H25N3O2S2
    (2S)-N-cyclohexyl-N-methyl-2-(4-oxo-3-phenylthieno[2,3-d]pyrimidin-2-yl)sulfanylpropanamide
    —— 1,3-dimethyl-6-[[(7R)-7-methyl-4-oxo-3-phenyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl]sulfanylmethyl]pyrimidine-2,4-dione —— C24H24N4O3S2
    1,3-dimethyl-6-[[(7R)-7-methyl-4-oxo-3-phenyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl]sulfanylmethyl]pyrimidine-2,4-dione
    —— 5-(4-fluorophenyl)-3-[2-[(2R)-2-methylmorpholin-4-yl]-2-oxoethyl]thieno[2,3-d]pyrimidin-4-one —— C19H18FN3O3S
    5-(4-fluorophenyl)-3-[2-[(2R)-2-methylmorpholin-4-yl]-2-oxoethyl]thieno[2,3-d]pyrimidin-4-one
    —— N-[(2R)-butan-2-yl]-2-(5-cyclopropyl-4-oxo-3-phenylthieno[2,3-d]pyrimidin-2-yl)sulfanylacetamide —— C21H23N3O2S2
    N-[(2R)-butan-2-yl]-2-(5-cyclopropyl-4-oxo-3-phenylthieno[2,3-d]pyrimidin-2-yl)sulfanylacetamide