Rhodosporidium toruloides

• 英文名称: Rhodosporidium toruloides

反应信息

• 作为试剂：
  描述：

  2-acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-D-mannopyranose 在 Rhodosporidium toruloides 作用下， 以 水 为溶剂， 反应 30.0h， 以46%的产率得到1,3,4-tri-O-acetyl-2-(acetylamino)-2-deoxy-α-D-mannopyranoside
  参考文献：
  名称：

  Comparison of chemical and enzymatic synthesis of 2-acetamido-2-deoxy-d-mannose 6-phosphate: a new approach

  摘要：

  Chemical and enzymatic methods to synthesis of 2-acetamido-2-deoxy-D-mannose-6-phosphate (ManNAc-6-P) have been investigated. A new preparative method has been developed although some established procedures were tried. In this new method, a 6-O-acetyl or 4,6-di-O-acetyl group of the per-O-acetylated 2-acetamido-2-deoxy-D-mannose (ManNAc) were regioselectively removed with an esterase from the yellow yeast, Rhonosporidium toruloides, followed by phosphorylation and O-deacetylation under mild conditions. H-1 and C-13 NMR data spectra of ManNAc-6-P were recorded. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0008-6215(00)00299-8