cinchona alkaloid C₂-DHQD-1

• 英文名称: cinchona alkaloid C₂-DHQD-1

反应信息

• 作为试剂：
  描述：

  1-乙酰氧基-1-环己基-2-丁烯 在 四氧化锇 、 cinchona alkaloid C₂-DHQD-1 potassium carbonate 、 potassium hexacyanoferrate(III) 作用下， 以 水 、 叔丁醇 为溶剂， 反应 48.0h， 生成 Acetic acid (E)-(S)-1-cyclohexyl-but-2-enyl ester 、 Acetic acid (1R,2R,3S)-1-cyclohexyl-2,3-dihydroxy-butyl ester 、 Acetic acid (1R,2S,3R)-1-cyclohexyl-2,3-dihydroxy-butyl ester
  参考文献：
  名称：

  Kinetic resolution of racemic allylic acetates by asymmetric dihydroxylation (ADH) process: An indication of π-π interaction

  摘要：

  Kinetic resolution of several racemic secondary allylic acetates have been examined using osmium tetroxide-cinchona alkaloid as chiral catalyst. The unexpected results have been rationalized with the help of model based on pi-pi interaction in the transition state apart from the matching and mismatching of the substrate and the catalyst.

  DOI：

  10.1016/s0040-4039(00)79261-6