trans-dichlorobis(5-amino-2-tert-butyltetrazole)palladium(II) | 1198428-00-0

• 英文名称: trans-dichlorobis(5-amino-2-tert-butyltetrazole)palladium(II)
• CAS: 1198428-00-0
• 化学式: C₁₀H₂₂Cl₂N₁₀Pd
• 分子量: 459.678
• InChiKey: OFCMFCFQIQXVEI-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  2-(1,1-二甲基乙基)-2H-四唑-5-胺 、 palladium(II) chloride dihydrate 在 HCl 作用下， 以 乙醇 、 水 为溶剂， 以94%的产率得到trans-dichlorobis(5-amino-2-tert-butyltetrazole)palladium(II)
  参考文献：
  名称：

  Copper(II), palladium(II) and platinum(II) chloride complexes with 5-amino-2-tert-butyltetrazole: Synthesis, characterization and cytotoxicity

  摘要：

  Complexes CuL3Cl2, PdL2Cl2 and PtL2Cl2, where L is a novel ligand from the series of 2-substituted 5-aminotetrazoles, namely 5-amino-2-tert-butyltetrazole (1), have been synthesized by the reaction of metal(II) chlorides with 1 and characterized by IR spectroscopy, thermal and X-ray analyses. The crystallographic structural analysis of these complexes revealed that I acts as a monodentate ligand coordinated to the metal via endocyclic N4 atom. Platinum complex demonstrates promising cytotoxicity against human cervical carcinoma cells with IC50 value average between those of cisplatin and carboplatin. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2009.07.054