(2S,5R)-N-{[(4S)-1H-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-4-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide | 1572987-93-9

• 英文名称: (2S,5R)-N-{[(4S)-1H-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-4-yl]methyloxy}-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide
• 英文别名: [(2S,5R)-7-oxo-2-[[(4S)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-4-yl]methoxycarbamoyl]-1,6-diazabicyclo[3.2.1]octan-6-yl] hydrogen sulfate
• CAS: 1572987-93-9
• 化学式: C₁₃H₁₈N₆O₇S
• 分子量: 402.388
• InChiKey: VMMSHGMYJKVGGO-ONOSFVFSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.7
• 重原子数：
  27
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  175
• 氢给体数：
  4
• 氢受体数：
  9

文献信息

• 1,6- DIAZABICYCLO [3,2,1] OCTAN-7-ONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIONS
  申请人：Patil Vijaykumar Jagdishwar

  公开号：US20150203503A1

  公开（公告）日：2015-07-23

  Compounds of Formula (I), their preparation and use in preventing or treating bacterial infections are disclosed.

  公式（I）化合物的制备和在预防或治疗细菌感染中的用途被披露。
• [EN] 1,6- DIAZABICYCLO [3,2,1] OCTAN- 7- ONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIONS<br/>[FR] DÉRIVÉS DE 1,6-DIAZABICYCLO[3,2,1]OCTAN-7-ONE ET LEUR UTILISATION DANS LE TRAITEMENT D'INFECTIONS BACTÉRIENNES
  申请人：WOCKHARDT LTD

  公开号：WO2014033560A1

  公开（公告）日：2014-03-06

  Compounds of Formula (I), their preparation and use in preventing or treating bacterial infections are disclosed.

  公开了化合物(I)的结构式，它们的制备方法以及在预防或治疗细菌感染中的用途。
• 1,6- DIAZABICYCLO [3,2,1] OCTAN- 7- ONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIONS
  申请人：WOCKHARDT LIMITED

  公开号：US20160213655A1

  公开（公告）日：2016-07-28

  Compounds of Formula (I), their preparation and use in preventing or treating bacterial infections are disclosed.

  公开了式（I）的化合物，它们的制备和用于预防或治疗细菌感染的用途。
• 1,6- DIAZABICYCLO [3,2,1]OCTAN- 7- ONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIONS
  申请人：Wockhardt Limited

  公开号：EP2961751A1

  公开（公告）日：2016-01-06
• US9732081B2
  申请人：——

  公开号：US9732081B2

  公开（公告）日：2017-08-15