4-Benzyloxy-1-ethylsulfanyl-2-methyl-benzene | 94571-11-6

• 英文名称: 4-Benzyloxy-1-ethylsulfanyl-2-methyl-benzene
• 英文别名: (4-(BenZyloxy)-2-methylphenyl)(ethyl)sulfane；1-ethylsulfanyl-2-methyl-4-phenylmethoxybenzene
• CAS: 94571-11-6
• 化学式: C₁₆H₁₈OS
• 分子量: 258.384
• InChiKey: DBMLZSIWRWRVOA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  34.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• SULFONAMIDE DERIVATIVES AS PPAR MODULATORS
  申请人：ELI LILLY AND COMPANY

  公开号：EP1597248A2

  公开（公告）日：2005-11-23
• [EN] SULFONAMIDE DERIVATIVES AS PPAR MODULATORS<br/>[FR] DERIVES DE SULFONAMIDES UTILISES COMME MODULATEURS DU RECEPTEUR PPAR
  申请人：LILLY CO ELI

  公开号：WO2004073606A2

  公开（公告）日：2004-09-02

  The present invention is directed to a compound of Formula (I):, and pharmaceutically acceptable salts, solvates, hydrates or stereoisomers thereof, which are useful in treating or preventing disorders mediated by a peroxisome proliferator activated receptor (PPAR) such as syndrome X, type II diabetes, hyperglycemia, hyperlipidemia, obesity, coagaulopathy, hypertension, arteriosclerosis, and other disorders related to syndrome X and cardiovascular diseases.