benzoyl(2-methyl-6-phenylpyridin-1-ium-1-yl)amide | 1020416-45-8

• 英文名称: benzoyl(2-methyl-6-phenylpyridin-1-ium-1-yl)amide
• CAS: 1020416-45-8
• 化学式: C₁₉H₁₆N₂O
• 分子量: 288.349
• InChiKey: LJQAZCGTNPBWJR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  2-methyl-N-benzoyliminopyridinium ylide 、 苯硼酸 在 dipotassium peroxodisulfate 、 四丁基溴化铵 、 silver nitrate 作用下， 以 二氯甲烷 、 水 为溶剂， 生成 benzoyl(2-methyl-6-phenylpyridin-1-ium-1-yl)amide 、
  参考文献：
  名称：

  Silver-Catalyzed Direct C–H Arylation of N-Iminopyridinium Ylides with Arylboronic Acids

  摘要：

  A novel direct C-H arylation of N-iminopyridinium ylides with arylboronic acids has been developed. This reaction is performed at ambient temperature using inexpensive reagents: catalytic silver nitrate in the presence of potassium persulfate co-oxidant and give pyridyl arylation derivatives in moderate to good yields.

  DOI：

  10.1055/s-0033-1341268

文献信息

• Palladium-Catalyzed Benzylic C−H Insertion of 2-Substituted <i>N</i>-Iminopyridinium Ylides
  作者：James J. Mousseau、Alexandre Larivée、André B. Charette

  DOI：10.1021/ol800396v

  日期：2008.4.1

  Palladium-catalyzed direct benzylic C-H arylation of 2-alkyl substituted N-iminopyridinium ylides is described. The insertion can be conducted with several electron-poor and electron-rich aryl chlorides in good yields. This work adds to the few examples of sp(3) C-H insertions that have been reported so far.