Pd2Cl2[6-methyl-2,2'-bipyridine]2 | 1212015-95-6

• 英文名称: Pd2Cl2[6-methyl-2,2'-bipyridine]2
• CAS: 1212015-95-6
• 化学式: C₂₂H₁₈Cl₂N₄Pd₂
• 分子量: 622.158
• InChiKey: TZFKSPJXDIHHBK-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  palladium diacetate 、 lithium chloride 、 6-甲基-2,2′-二吡啶 以 toluene 为溶剂， 以66%的产率得到Pd2Cl2[6-methyl-2,2'-bipyridine]2
  参考文献：
  名称：

  Step by step palladium mediated syntheses of new 2-(pyridin-2-yl)-6-R-nicotinic acids and esters

  摘要：

  Taking advantage of palladium peculiar "rollover" C, N cyclometallation, it is possible to promote C(3) functionalization of 6-alkyl-substituted-2,2'-bipyridines. The carbonylation reaction of rollover species [Pd(L-n)Cl](2), (HL1 = 6-isopropyl-2,2'-bipy, 1; HL2 = 6-neopentyl-2,2'-bipy, 2; HL3 = 6-ethyl-2,2'-bipy, 3; HL4 = 6-methyl-2,2'-bipy, 4) allowed the synthesis of 2-(pyridin-2-yl)-6-alkyl-nicotinic acids or esters. These nicotinic derivatives are extremely rare and, as far as we know, quite unreported in the case of the 6-substituted molecules. (C) 2009 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2009.10.002