| 875540-54-8

• CAS: 875540-54-8
• 化学式: C₁₈H₂₂ClCuN₄O₃*ClO₄
• 分子量: 540.847
• InChiKey: OYVSLQSQFYPNIB-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  sodium perchlorate monohydrate 、 、 copper dichloride 以 甲醇 为溶剂， 以40%的产率得到
  参考文献：
  名称：

  Interaction between Cu(II) Compounds and Amyloid β‐peptide (1–40) in Solution

  摘要：

  Capillary electrophoresis (CE) and ESR spectral measurements have revealed that amyloid beta-peptide ( 1 - 40) interacts with the copper( II)-(dpgt)complex specifically in solution, leading to an aggregation of the Cu( II)- complex, but the analogous copper complex with (dpa-GMe) did not aggregate under the same experimental conditions, where ( dpgt) representsN,N-bis(2-pyridylmethyl) glycylglycylglycine. These facts seem to be very important to elucidate the origin of the abnormal storage of the metal ions such as copper or iron ions in the senile plaques of Alzheimer's disease patients brain tissue.

  DOI：

  10.1081/sim-200059209