| 869337-51-9

• CAS: 869337-51-9
• 化学式: C₆H₂₀B₁₀O₂
• 分子量: 232.334
• InChiKey: RZBSYCAWOIMUIB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  在 甲酸 作用下， 以 甲酸 为溶剂， 以76%的产率得到2-(o-carboranyl)ethanal
  参考文献：
  名称：

  Simple, High-Yield Methods for the Synthesis of Aldehydes Directly from o-, m-, and p-Carborane and Their Further Conversions

  摘要：

  Aldehydes have long served as important building blocks for synthetic chemists, and carboranyl aldehydes are no exception. Recent literature reports, for example, illustrate their application as intermediates in biomedicine, materials science, and basic organic chemistry. We report here new methods for the single-step preparation of C-monoformyl and C,C-diformyl derivatives directly from o-, m-, and p-carborane, as well as improved synthetic routes to homologated carboranyl aldehydes. Additionally, reductive amination is used to transform these aldehydes into a series of 2 degrees amines of alpha-amino acid esters.

  DOI：

  10.1021/ic0506660
• 作为产物：
  描述：

  2-溴-1,1-二甲氧基乙烷 、 1,2-dicarba-closo-dodecaborane(12) 在 正丁基锂 作用下， 以 乙醚 、 正己烷 为溶剂， 生成
  参考文献：
  名称：

  Simple, High-Yield Methods for the Synthesis of Aldehydes Directly from o-, m-, and p-Carborane and Their Further Conversions

  摘要：

  Aldehydes have long served as important building blocks for synthetic chemists, and carboranyl aldehydes are no exception. Recent literature reports, for example, illustrate their application as intermediates in biomedicine, materials science, and basic organic chemistry. We report here new methods for the single-step preparation of C-monoformyl and C,C-diformyl derivatives directly from o-, m-, and p-carborane, as well as improved synthetic routes to homologated carboranyl aldehydes. Additionally, reductive amination is used to transform these aldehydes into a series of 2 degrees amines of alpha-amino acid esters.

  DOI：

  10.1021/ic0506660