CoCl2(N,N'-bis(4-isopropylbenzaldimine)-1,2-diaminoethane)2 | 1334551-05-1

• 英文名称: CoCl2(N,N'-bis(4-isopropylbenzaldimine)-1,2-diaminoethane)2
• CAS: 1334551-05-1
• 化学式: C₄₄H₅₆Cl₂CoN₄
• 分子量: 770.855
• InChiKey: IRWMCUQHXGCDAJ-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  N,N-bis(4-isopropylbenzylidene)ethane-1,2-diamine 、 cobalt(II) chloride 以 甲醇 为溶剂， 以78%的产率得到CoCl2(N,N'-bis(4-isopropylbenzaldimine)-1,2-diaminoethane)2
  参考文献：
  名称：

  Synthesis, spectroscopic, antimicrobial, DNA binding and cleavage studies of some metal complexes involving symmetrical bidentate N, N donor Schiff base ligand

  摘要：

  The Schiff base ligand, N,N'-bis-(4-isopropylbenzaldimine)-1,2-diaminoethane (L), obtained by the condensation of 4-isopropylbenzaldehyde and 1,2-diaminoethane, has been used to synthesize the complexes of the type [ML(2)X(2)] [M = Co(II), Ni(II) and Zn(II); X = Cl and OAc]. The newly synthesized ligand (L) and its complexes have been characterized on the basis of elemental analyses, mass, (1)H and (13)C-NMR, molar conductance, IR, UV-vis, magnetic moment, CV and thermal analyses, powder XRD and SEM. IR spectral data show that the ligand is coordinated to the metal ions in a bidentate manner. The geometrical structures of these complexes are found to be octahedral. Interestingly, reaction with Cu(II) ion with this ligand undergoes hydrolytic cleavage to form ethylenediamine copper(II) complex and the corresponding aldehyde. The antimicrobial results indicate that the chloro complexes exhibit more activity than the acetato complexes. The complexes bind to CT-DNA by intercalation modes. Novel chloroform soluble ZnL(2)Cl(2) complex exhibits tremendous antimicrobial. DNA binding and cleaving properties. (C) 2011 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2011.07.031