1β,6β-Diacetoxy-7β,15α-dihydroxy-7,20-epoxy-5β,9β-kauren | 16633-40-2

• 英文名称: 1β,6β-Diacetoxy-7β,15α-dihydroxy-7,20-epoxy-5β,9β-kauren
• CAS: 16633-40-2
• 化学式: C₂₄H₃₄O₇
• 分子量: 434.53
• InChiKey: ABGYNGKHRAYOJK-XMZPRCKDSA-N

物化性质

• 熔点：
  175-178 °C
• 沸点：
  553.1±50.0 °C(Predicted)
• 密度：
  1.29±0.1 g/cm3(Predicted)

反应信息

• 作为反应物：
  描述：

  1β,6β-Diacetoxy-7β,15α-dihydroxy-7,20-epoxy-5β,9β-kauren 在 lithium aluminium tetrahydride 作用下， 以 乙醚 为溶剂， 生成 1β,6β,7β,15α-Tetrahydroxy-7,20-epoxy-5β,9β-kauren
  参考文献：
  名称：

  Terpenoids. XXXIII. Chemical conversion of enmein into enmelol.

  摘要：

  After several preliminary experiments, enmein (1) was converted into enmelol (2). The route consists of the following steps : (i) Enmein (1) was converted into lactone ester 40 via 3, 8, 9, and 10. (ii) An acyloin product 42 derived from 40 was transformed into 15-kaurene derivative 61, via epoxide 56, 1β-ol 57, acetate 58, and 15-ol 59. (iii) By photosensitized oxygenation of 61, allyl alcohol 62 and αβ-unsaturated ketone 63 were yielded. (iv) Enmelol (2) and 15-epienmelol (69) were derived from 63 and 62, respectively.

  DOI：

  10.1248/cpb.23.858
• 作为产物：
  描述：

  在 吡啶 、 盐酸 、 甲基磺酰氯 作用下， 以 甲醇 为溶剂， 生成 1β,6β-Diacetoxy-7β,15α-dihydroxy-7,20-epoxy-5β,9β-kauren
  参考文献：
  名称：

  Terpenoids. XXXIII. Chemical conversion of enmein into enmelol.

  摘要：

  After several preliminary experiments, enmein (1) was converted into enmelol (2). The route consists of the following steps : (i) Enmein (1) was converted into lactone ester 40 via 3, 8, 9, and 10. (ii) An acyloin product 42 derived from 40 was transformed into 15-kaurene derivative 61, via epoxide 56, 1β-ol 57, acetate 58, and 15-ol 59. (iii) By photosensitized oxygenation of 61, allyl alcohol 62 and αβ-unsaturated ketone 63 were yielded. (iv) Enmelol (2) and 15-epienmelol (69) were derived from 63 and 62, respectively.

  DOI：

  10.1248/cpb.23.858