(2-bromo-3,4,5,6-tetrafluorophenyl)bis(triethyl-l5-phosphaneyl)nickel(IV) bromide | 161587-81-1

• 英文名称: (2-bromo-3,4,5,6-tetrafluorophenyl)bis(triethyl-l5-phosphaneyl)nickel(IV) bromide
• CAS: 161587-81-1
• 化学式: C₁₈H₃₀Br₂F₄NiP₂
• 分子量: 602.875
• InChiKey: XPNOUMXOYLJISA-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
  None
• sp3杂化的碳原子比例：
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• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  (2-bromo-3,4,5,6-tetrafluorophenyl)bis(triethyl-l5-phosphaneyl)nickel(IV) bromide 在 lithium 作用下， 以 乙醚 为溶剂， 生成 Ni((1,2-η)-C6F4)(PEt3)2
  参考文献：
  名称：

  苯炔-镍（0）配合物与乙炔的插入反应

  摘要：

  Complexes of nickel(0) containing eta(2)-4,5-difluorobenzyne, Ni((1,2-eta)-4,5-F2C6H2)(PEt(3))(2) (10) and Ni((1,2-eta)-4,5-F2C6H2)(dcpe) (11; dcpe = 1,2-bis(dicyclohexylphosphino)ethane, Cy(2)PCH(2)-CH(2)PCy(2)) have been synthesized by alkali-metal reduction of the appropriate (2-halo-genoaryl)nickel(II) halides. Spectroscopic measurements (C-13 NMR, FAB-MS) indicate that 10, 11, and the parent benzyne complex Ni((1,2-eta)-C6H4)(PEt(3))(2) (2) are monomeric, analogous to the structurally characterized species Ni((1,2-eta)-C6H4)(Cy(2)PCH(2)CH(2)PCy(2)). Complexes 2 and 10 undergo rapid intermolecular exchange with PEt(3) at room temperature and react with disubstituted acetylenes by double insertion into the metal-benzyne bond to form 1,2,3,4-tetrasubstituted naphthalenes. With electrophilic acetylenes (MeO(2)CC(2)CO(2)Me, MeC(2) . CO(2)Me, HC(2)CO(2)Me, and CF3C2CF3) an aromatic cyclotrimer is also formed; exceptionally, hexafluorobut-2-yne also gives with 10 a phenanthrene derived from two benzyne units and the acetylene. The unsymmetrical acetylenes tert-butylacetylene and methyl 2-butynoate give rise to good regioselectivity in the resulting naphthalenes, the favored isomers being very dependent on the steric and electronic influence of the substituents. The dcpe complexes react similarly but more slowly with acetylenes, and with MeO(2)CC(2)CO(2)Me the monoinsertion complexes Ni{C(CO(2)Me)=C(CO(2)Me)C(6)H(2)R(2)-o}(dcpe) (R = H, F) can be observed.

  DOI：

  10.1021/om00003a029
• 作为产物：
  描述：

  三乙基膦 、 bis(1,5-cyclooctadiene)nickel (0) 、 1,2-二溴四氟苯 以 正己烷 为溶剂， 以57%的产率得到(2-bromo-3,4,5,6-tetrafluorophenyl)bis(triethyl-l5-phosphaneyl)nickel(IV) bromide
  参考文献：
  名称：

  苯炔-镍（0）配合物与乙炔的插入反应

  摘要：

  Complexes of nickel(0) containing eta(2)-4,5-difluorobenzyne, Ni((1,2-eta)-4,5-F2C6H2)(PEt(3))(2) (10) and Ni((1,2-eta)-4,5-F2C6H2)(dcpe) (11; dcpe = 1,2-bis(dicyclohexylphosphino)ethane, Cy(2)PCH(2)-CH(2)PCy(2)) have been synthesized by alkali-metal reduction of the appropriate (2-halo-genoaryl)nickel(II) halides. Spectroscopic measurements (C-13 NMR, FAB-MS) indicate that 10, 11, and the parent benzyne complex Ni((1,2-eta)-C6H4)(PEt(3))(2) (2) are monomeric, analogous to the structurally characterized species Ni((1,2-eta)-C6H4)(Cy(2)PCH(2)CH(2)PCy(2)). Complexes 2 and 10 undergo rapid intermolecular exchange with PEt(3) at room temperature and react with disubstituted acetylenes by double insertion into the metal-benzyne bond to form 1,2,3,4-tetrasubstituted naphthalenes. With electrophilic acetylenes (MeO(2)CC(2)CO(2)Me, MeC(2) . CO(2)Me, HC(2)CO(2)Me, and CF3C2CF3) an aromatic cyclotrimer is also formed; exceptionally, hexafluorobut-2-yne also gives with 10 a phenanthrene derived from two benzyne units and the acetylene. The unsymmetrical acetylenes tert-butylacetylene and methyl 2-butynoate give rise to good regioselectivity in the resulting naphthalenes, the favored isomers being very dependent on the steric and electronic influence of the substituents. The dcpe complexes react similarly but more slowly with acetylenes, and with MeO(2)CC(2)CO(2)Me the monoinsertion complexes Ni{C(CO(2)Me)=C(CO(2)Me)C(6)H(2)R(2)-o}(dcpe) (R = H, F) can be observed.

  DOI：

  10.1021/om00003a029