| 1355693-49-0

• CAS: 1355693-49-0
• 化学式: C₁₄H₁₇Cl₂N₃Zn
• 分子量: 363.605
• InChiKey: YWBVXQIYIMHMQZ-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  N¹,N¹-dimethyl-N⁴-(pyridin-2-ylmethyl)benzene-1,4-diamine 、 zinc(II) chloride 以 甲醇 、 乙醚 为溶剂， 以79%的产率得到
  参考文献：
  名称：

  Characterization of pyridinylimine and pyridinylmethylamine derivatives and their corresponding metal complexes

  摘要：

  Bidentate pyridinylimine (L1-a and L1-b) and pyridinylmethylamine (L2-a and L2-b) derivatives have recently received attention due to their potential use as chemical reagants that can target metal-associated amyloid-beta (A beta) species and modulate metal-induced A beta aggregation and neurotoxicity in vitro and in living cells. Herein, we report the characterization of these bidentate ligands and their corresponding metal complexes by X-ray crystallography and spectroscopic methods, including UV-Vis spectroscopy (UV-Vis), nuclear magnetic resonance spectroscopy (NMR), and Fourier transform infrared spectroscopy (FT-IR). Our studies presented how the different structural moieties of ligand frameworks (L1-a, L1-b, L2-a, and L2-b), in addition to effects of metal binding, contribute to variations in structure and chemical environments of the ligands and their corresponding metal complexes. (C) 2011 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2011.08.056