| 1397718-09-0

• CAS: 1397718-09-0
• 化学式: C₄₆H₆₄Fe₂N₆O₈S₂
• 分子量: 1004.88
• InChiKey: IUPIMTHNBLTZFH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  胱胺 、 在 HBTU 、 Et₃N 作用下， 以 二氯甲烷 为溶剂， 以72%的产率得到
  参考文献：
  名称：

  Synthesis of a series of 1,n′-disubstituted ferrocene derivatives containing disulfides

  摘要：

  A series of ferrocene amide cystamine derivatives was prepared from 1'-methoxycarbonylferrocene-1-carboxylic acid in a step-wise fashion, via amide bond formation with a series of Boc-protected diamines, followed by coupling to cystamine. The length of the diamine linker was varied systematically from 2 to 10 methylene groups. All products were characterized spectroscopically. In solution, all ferrocene compounds displayed a quasi-reversible ferrocene/ferrocenium redox couple between 258 and 320 mV versus external Fc/Fc(+). The Boc-protected ethylene diamine ferrocene conjugate 7 was characterized by single crystal X-ray crystallography. Intermolecular hydrogen bonding exists between amide groups of adjacent molecules. The presence of the disulfide group allows chemisorption of Fc-conjugates 18-22 onto gold surfaces. Electrochemical measurements allow an evaluation of the electron transfer kinetics using the Butler-Volmer formalism. Electron transfer rate constants were determined to be in the range of 1.871(67)-2.105(258) s(-1). (C) 2012 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2012.05.013