| 1190849-21-8

• CAS: 1190849-21-8
• 化学式: C₂₈H₂₃FeP
• 分子量: 447.303
• InChiKey: WUJXTKZFDKVKDR-IPPMSNHBSA-N

反应信息

• 作为反应物：
  描述：

  sodium tetrachloropalladate(II) 、 在 sodium hydroxide 作用下， 以 甲醇 、 二氯甲烷 、 水 为溶剂， 生成 chloropalladium(1+);cyclopenta-1,3-diene;(2-cyclopenta-2,4-dien-1-ylphenyl)-diphenylphosphane;iron(2+)
  参考文献：
  名称：

  Synthesis of Planar Chiral Phosphapalladacycles by N-Acyl Amino Acid Mediated Enantioselective Palladation

  摘要：

  Reaction of 2-(dicyclohexcylphosphino)phenylferrocene with sodium tetrachloropalladate in the presence of 1 equiv of (R)-N-acetylphenylalamine in MeOH/H2O/CH2Cl2 at pH 8 resulted in the formation of bis(mu-chloro)bis-[2-(2-(dicyclohexylphosphino)phenyl)ferrocene-C-I, P]dipalladium(II) with a 59% enantiomeric excess of the S-p planar chiral palladacycle. Similarly, (dimethylamitionmethyl)ferrocene gave (S-p)-bis-(mu-chloro)bis[2-(dimethylaminomethyl)ferrocene-C-I, P]-dipalladium(II) in 96% ee. An intramolecular isotope effect of 2.3 was observed for the palladation of 2-(diphenylphosphino)phenylferrocene under these conditions.

  DOI：

  10.1021/om9005356
• 作为产物：
  描述：

  lithium aluminium deuteride 、 chloropalladium(1+);cyclopenta-1,3-diene;(2-cyclopenta-2,4-dien-1-ylphenyl)-diphenylphosphane;iron(2+) 以 乙醚 为溶剂， 以74%的产率得到
  参考文献：
  名称：

  Synthesis of Planar Chiral Phosphapalladacycles by N-Acyl Amino Acid Mediated Enantioselective Palladation

  摘要：

  Reaction of 2-(dicyclohexcylphosphino)phenylferrocene with sodium tetrachloropalladate in the presence of 1 equiv of (R)-N-acetylphenylalamine in MeOH/H2O/CH2Cl2 at pH 8 resulted in the formation of bis(mu-chloro)bis-[2-(2-(dicyclohexylphosphino)phenyl)ferrocene-C-I, P]dipalladium(II) with a 59% enantiomeric excess of the S-p planar chiral palladacycle. Similarly, (dimethylamitionmethyl)ferrocene gave (S-p)-bis-(mu-chloro)bis[2-(dimethylaminomethyl)ferrocene-C-I, P]-dipalladium(II) in 96% ee. An intramolecular isotope effect of 2.3 was observed for the palladation of 2-(diphenylphosphino)phenylferrocene under these conditions.

  DOI：

  10.1021/om9005356