[(ferrocene-1,1'-diyl)bis[2-[(2-ethylidenhydrazinyliden-_κN2)]-methyl]phenolato]palladium | 1446344-15-5

• 英文名称: [(ferrocene-1,1'-diyl)bis[2-[(2-ethylidenhydrazinyliden-_κN2)]-methyl]phenolato]palladium
• 英文别名: (ferrocene-1,1'-diyl)bis[2-[(2-ethylidenhydrazinyliden-_KN₂)-methyl]phenolato]palladium
• CAS: 1446344-15-5
• 化学式: C₂₈H₂₄FeN₄O₂Pd
• 分子量: 610.791
• InChiKey: BJAJJINVPIGNOC-UHFFFAOYSA-L

反应信息

• 作为产物：
  描述：

  1,1'-bis[1-[2-[(2-hydroxyphenyl)methylene]-hydrazinylidene]-ethyl]-ferrocene 、 palladium dichloride 以 乙醇 为溶剂， 反应 3.0h， 以82%的产率得到[(ferrocene-1,1'-diyl)bis[2-[(2-ethylidenhydrazinyliden-_κN2)]-methyl]phenolato]palladium
  参考文献：
  名称：

  Hegazy, Wael; Al-Faiyz, Yasair Suliman, Journal of the Chemical Society of Pakistan, 2013, vol. 35, # 5, p. 1312 - 1318

  摘要：

  DOI：

文献信息

• Synthesis, characterization, and antitumor activities of 1,1′-diacetylferrocene dihydrazone containing phenolic group and its complexes with Pd(II) and Pt(II)
  作者：Wael Hussein Hegazy、Yasair Suliman Al-Faiyz

  DOI：10.1007/s00044-013-0661-x

  日期：2014.1

  A ferrocenyl ligand was prepared from condensation of 1,1'-diacetylferrocene dihydrazone with salicylaldehyde. The ligand forms 1:1 complexes with Pd(II) and Pt(II) in good yield. Characterization of the ligand and complexes was carried out using elemental analysis, infrared study, H-1 and C-13 nuclear magnetic resonance, and electronic absorption spectra. Anticancer activity of the prepared ligand and its complexes against human breast cancer cell line MCF-7 was determined, and the results were compared with the activity of the commonly used anticancer drug cisplatin. The results suggested that the prepared compounds possess significant antitumor activity comparable to the activity of cisplatin.