[RuCl2(2-[2-(diphenylphosphino)phenyl]-4,5-dihydro-1,3-oxazole)2] | 1609187-33-8

• 英文名称: [RuCl2(2-[2-(diphenylphosphino)phenyl]-4,5-dihydro-1,3-oxazole)2]
• 英文别名: [RuCl₂(2-[2-(diphenylphosphino)phenyl]-4,5-dihydro-1,3-oxazole)₂]
• CAS: 1609187-33-8
• 化学式: C₄₂H₃₆Cl₂N₂O₂P₂Ru
• 分子量: 834.684
• InChiKey: CFUTUZABAUAYHL-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  2-(2-(diphenylphosphaneyl)phenyl)-4,5-dihydrooxazole 、 tetrakis(dimethylsulfoxide)dichlororuthenium(II) 以 甲苯 为溶剂， 反应 48.0h， 以82%的产率得到[RuCl2(2-[2-(diphenylphosphino)phenyl]-4,5-dihydro-1,3-oxazole)2]
  参考文献：
  名称：

  Ruthenium complexes of the general formula [RuCl2(PHOX)2] and their catalytic activity in the Mukaiyama aldol reaction

  摘要：

  New ruthenium phosphinooxazoline (PHOX) complexes were synthesized and applied in the Mukaiyama aldol reaction. Four ruthenium complexes of the general formula [RuCl2(PHOX)(2)] were synthesized from [RuCl2(dmso)(4)] and the corresponding PHOX ligands through thermal ligand exchange. Two of the complexes were characterized structurally. Achiral PHOX ligands gave the ruthenium complexes as single isomers, whereas chiral PHOX ligands gave a mixture of isomers and also some incomplete substitution. After activation by chloride abstraction, one of the new ruthenium complexes was applied as catalyst in the Mukaiyama aldol reaction to give silyl-protected 13-hydroxyl alcohols in 74-92% isolated yields (room temperature, 18-24 h reaction time, 1 mol % catalyst loading). (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2014.03.111