[PdCl(C6H4CH2NMe2)(2-(bis(3,5-dimethylphenyl)phosphino)-1,1'-binaphthyl)] | 701284-56-2

• 英文名称: [PdCl(C6H4CH2NMe2)(2-(bis(3,5-dimethylphenyl)phosphino)-1,1'-binaphthyl)]
• CAS: 701284-56-2
• 化学式: C₄₅H₄₃ClNPPd
• 分子量: 770.69
• InChiKey: OCVNJJGAJNNUMC-UHFFFAOYSA-M

反应信息

• 作为产物：
  描述：

  bis[(benzyldimethylamino)chloropalladium(II)] 、 2-(bis(3,5-dimethylphenyl)phosphino)-1,1'-binaphthyl 以 二氯甲烷 为溶剂， 以56%的产率得到[PdCl(C6H4CH2NMe2)(2-(bis(3,5-dimethylphenyl)phosphino)-1,1'-binaphthyl)]
  参考文献：
  名称：

  3,5-Dialkyl Effect on Enantioselectivity in Pd Chemistry:  Applications Involving Both Bidentate and Monodentate Auxiliaries

  摘要：

  The structural 3,5-dialkylphenyl effect on enantioselectivity is demonstrated for several Pd-catalyzed reactions including a ring-opening transmetalation, Heck arylation, and allylic alkylation. For these homogeneously catalyzed reactions the observed enantiomeric excesses (ee's) are found to improve by more than 15%. The ligands tested include MeO-Biphep and a P,N-phosphino-oxazoline-bidentate ligand containing 3,5-di-tert-butylphenyl substituents. Further, several derivatives of the monodentate auxiliary MOP ((R)-2-diarylphosphino-1,1'-binaphthyl) have been modified to include 3,5-dialkylphenyl substituents and these auxiliaries have been tested in Pd-catalyzed enantioselective hydrosilylation chemistry. For some, but not all of these MOP ligands, enhanced ee's of the order of 40-50% are found. Variable-temperature and 2-D NMR studies have been carried out on new model complexes and reveal selected restricted rotation around a number of the P-C(Ipso) aryl bonds. Solid-state structures for two of the new complexes, PdBr(p-NCC6H4)(phosphino-oxazoline, 2b), 8b, and PdCl(C6H4CH2NMe2)(MOP, 4b), 9b, have been determined.

  DOI：

  10.1021/om034381b