| 1291069-19-6

• CAS: 1291069-19-6
• 化学式: C₅₇H₃₇BF₂N₂O₄
• 分子量: 862.74
• InChiKey: CSEZOUYKNUVKPG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  methyl 4-[(Z)-(6'-methoxyspiro[fluorene-9,4'-indeno[1,2-b]pyrrole]-2'-ylidene)-(6-methoxyspiro[1H-indeno[1,2-b]pyrrole-4,9'-fluorene]-2-yl)methyl]benzoate 在 三氟化硼乙醚 、 N,N-二异丙基乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 2.0h， 以152 mg的产率得到
  参考文献：
  名称：

  Near-infrared BODIPY dyes modulated with spirofluorene moieties

  摘要：

  New structurally constrained BODIPY dyes having electron-donating substituents were synthesized. As the key compounds for the construction of the BODIPY dyes, 1'H-spiro-[fluorene-9,4'-indeno[1,2-b] pyrrole] (sp-FIP) derivatives with electron-donating groups, such as OMe and NMe2 at its 6'-position, were prepared using palladium-catalyzed intramolecular direct C-H arylation of a pyrrole moiety. The resulting BODIPY dyes showed bathochromic shift in absorption and fluorescence spectra in comparison to the unsubstituted analogs. Furthermore, pH-dependent reversible spectrum changes of the BODIPY dye were observed with the addition of trifluoroacetic acid (TFA) and subsequent addition of i-Pr2NEt. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.02.073