| 1310449-87-6

• CAS: 1310449-87-6
• 化学式: C₁₈H₂₁ClN₃O₂RuS*Cl
• 分子量: 515.426
• InChiKey: KNIKMHJYRKOEDF-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  [bis((μ-chloro)chloro(η6-phenylbutyric acid)ruthenium(II))] 、 苯甲醛缩氨基硫 以75%的产率得到
  参考文献：
  名称：

  Mono- and dinuclear (η6-arene) ruthenium(II) benzaldehyde thiosemicarbazone complexes: Synthesis, characterization and cytotoxicity

  摘要：

  A series of mono- and dinuclear (eta(6)-arene) ruthenium(II) complexes were prepared by reaction of thiosemicarbazone ligands derived from benzaldehyde and ruthenium(II) precursors of the general formula [Ru(eta(6)-arene)(mu-Cl)Cl](2), where arene = p-(PrC6H4Me)-Pr-i or C6H5C3H6COOH. These complexes were characterized by NMR and IR spectroscopy, ESI-mass spectrometry and elemental analysis. The molecular structure of the mononuclear p-cymene complex was determined by X-ray diffraction analysis, revealing a pseudo-tetrahedral piano stool conformation and a bidentate N,S coordination mode of the thiosemicarbazone ligand. The complexes and ligands were evaluated for their in vitro cytotoxicity against the WHCO1 oesophageal cancer cell line. (C) 2011 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.inoche.2011.03.041