8-[3α,17β-bis(acetyloxy)-2β-(1-piperidinyl)-5α-androstan-16β-yl]-8-methyl-1,4-dioxa-8-azoniaspiro[4.5]decane bromide | 159325-40-3

• 英文名称: 8-[3α,17β-bis(acetyloxy)-2β-(1-piperidinyl)-5α-androstan-16β-yl]-8-methyl-1,4-dioxa-8-azoniaspiro[4.5]decane bromide
• 英文别名: [(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-17-acetyloxy-10,13-dimethyl-16-(8-methyl-1,4-dioxa-8-azoniaspiro[4.5]decan-8-yl)-2-piperidin-1-yl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate;bromide
• CAS: 159325-40-3
• 化学式: Br*C₃₆H₅₉N₂O₆
• 分子量: 695.778
• InChiKey: FEUKHQPCTZQDCQ-MHLFSCIFSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  2.32
• 重原子数：
  45
• 可旋转键数：
  6
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  74.3
• 氢给体数：
  0
• 氢受体数：
  8

文献信息

• Androstane derivatives substituted by a quaternary ammonium group in 16-position, pharmaceutical compositions containing them and process for preparing same
  申请人：Maruishi Pharmaceutical Co., Ltd.

  公开号：EP0608495B1

  公开（公告）日：1997-06-04
• US5591735A
  申请人：——

  公开号：US5591735A

  公开（公告）日：1997-01-07