| 1426437-80-0

• CAS: 1426437-80-0
• 化学式: C₂₄H₂₂AuNP*F₆Sb
• 分子量: 788.126
• InChiKey: ZPWPJSMRVHPVCY-UHFFFAOYSA-H

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  、 以 氘代氯仿 为溶剂， 生成 4-甲基吡啶 、
  参考文献：
  名称：

  Quantitative Evaluation of the Stability of gem-Diaurated Species in Reactions with Nucleophiles

  摘要：

  The reactivity of diaurated species toward nucleophiles was investigated. The reaction yields vinyl gold species and is described as simple S(N)2 ligand exchange at gold. Using suitably strong nucleophiles, equilibrium constants were determined to measure the stability of various diaurated species. On the basis of these equilibrium constants the influence of ligand and the nature of vinyl cores on the stability were analyzed. These results have direct implication for gold catalysis: it was demonstrated that vinyl gold intermediates bind the catalytic LAu+ species generally stronger than an alkyne (the substrate) by a factor of 10(6)-10(9). This demonstrates that the formation of diaurated species from vinyl gold intermediates is thermodynamically favored in a catalytic reaction.

  DOI：

  10.1021/om400083f
• 作为产物：
  描述：

  [(MeCN)Ph₃PAu]SbF₆ 、 Au(4-picoline)(tBu)2P(C6H4C6H5) 以 氘代氯仿 为溶剂， 生成 (乙腈)[(2-联苯)二叔丁基膦]六氟锑酸金(I) 、
  参考文献：
  名称：

  Quantitative Evaluation of the Stability of gem-Diaurated Species in Reactions with Nucleophiles

  摘要：

  The reactivity of diaurated species toward nucleophiles was investigated. The reaction yields vinyl gold species and is described as simple S(N)2 ligand exchange at gold. Using suitably strong nucleophiles, equilibrium constants were determined to measure the stability of various diaurated species. On the basis of these equilibrium constants the influence of ligand and the nature of vinyl cores on the stability were analyzed. These results have direct implication for gold catalysis: it was demonstrated that vinyl gold intermediates bind the catalytic LAu+ species generally stronger than an alkyne (the substrate) by a factor of 10(6)-10(9). This demonstrates that the formation of diaurated species from vinyl gold intermediates is thermodynamically favored in a catalytic reaction.

  DOI：

  10.1021/om400083f