trans-bis[(5-amino-8-methyl-4H-benzopyran-4-one-κ2-N,O)(perchlorato-κO)]copper(II) | 1352310-14-5

• 英文名称: trans-bis[(5-amino-8-methyl-4H-benzopyran-4-one-κ2-N,O)(perchlorato-κO)]copper(II)
• CAS: 1352310-14-5
• 化学式: C₂₀H₁₈Cl₂CuN₂O₁₂
• 分子量: 612.821
• InChiKey: ADWZBUMUOCIMLW-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  copper(II) perchlorate hexahydrate 、 5-amino-8-methyl-4H-benzopyran-4-one 以 甲醇 、 乙酸乙酯 为溶剂， 以28.3%的产率得到trans-bis[(5-amino-8-methyl-4H-benzopyran-4-one-κ2-N,O)(perchlorato-κO)]copper(II)
  参考文献：
  名称：

  Synthesis, structure, electrochemical properties, cytotoxic effects and antioxidant activity of 5-amino-8-methyl-4H-benzopyran-4-one and its copper(II) complexes

  摘要：

  The chromone derivative 5-amino-8-methyl-4H-benzopyran-4-one (ligand) (1) has been used to obtain a series of Cu(II) complexes 2-4 as potential anticancer compounds. The molecular structures of ligand 1 and its Cu(II) complex 3 have been determined by X-ray crystallography. The cytotoxicity of all obtained compounds has been evaluated on melanoma A375 cell line. The ability of compounds 1-4 to take part in redox reactions and their antioxidant activity have been studied. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2011.09.003