(S)-methoxy(tert-butyl)phenylphosphane-borane (1/1) | 690670-65-6

• 英文名称: (S)-methoxy(tert-butyl)phenylphosphane-borane (1/1)
• CAS: 690670-65-6
• 化学式: C₁₁H₂₀BOP
• 分子量: 210.064
• InChiKey: AFAXYOMXUWOAMS-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  (1S,2S)-2-[[(S)-(tert-butyl)phenylphosphanyl]methylamino]-1-phenylpropan-1-ol-P-borane (1/1) 在 H₂SO₄ 作用下， 以 甲醇 为溶剂， 以0%的产率得到(S)-methoxy(tert-butyl)phenylphosphane-borane (1/1)
  参考文献：
  名称：

  Formation of Diastereoisomerically Pure Oxazaphospholes and Their Reaction to Chiral Phosphane-Borane Adducts

  摘要：

  Starting with achiral phosphines and (1S,2S)-2-(methylamino)-1-phenylpropan-1-ol ((+)-pseudoephedrine) or (1R,2S)-2-(methylamino)-1-phenylpropan-1-ol ((-)-ephedrine), as chiral auxiliaries, diastereoisomerically pure oxazaphospholes wore prepared (Scheme 1). The configuration at the P-atom is controlled by the configuration at the Ph-substituted C(1) of (+)-pseudoephedrine or (-)-ephedrine, respectively. This was confirmed by X-ray crystal-structure analyses of two intermediate compounds in the synthesis route to the chiral triarylborane-phosphane adducts.

  DOI：

  10.1002/(sici)1522-2675(20000216)83:2<311::aid-hlca311>3.0.co;2-i