| 173174-14-6

• CAS: 173174-14-6
• 化学式: C₃₂H₃₄Au₂Cl₂N₂O₂P₂
• 分子量: 1005.42
• InChiKey: QXZDVYLZMLUXEQ-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
  None
• 氢给体数：
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• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  氯(二甲基硫化)金(I) 、 N,N'-(Ethane-1,2-diyl)bis[3-(diphenylphosphanyl)propanamide] 以 not given 为溶剂， 以95%的产率得到
  参考文献：
  名称：

  Dendrimer-Based Multinuclear Gold(I) Complexes

  摘要：

  In model reactions for the synthesis of phosphine-terminated tentacles of polyamine dendrimers, the amides MeNHCOC(2)H(4)PPh(2) (2a) and (CH(2)NHCOC(2)H(4)PPh(2))(2) (2b) were prepared from the spacer phosphine (diphenylphosphino)propionic acid (1) and methylamine or ethylenediamine, respectively, using EDC [N-ethyl-N'-(3-(dimethylamino)propyl)carbodiimide hydrochloride] as a coupling agent. By the same procedure, the dendritic, multifunctional species DAB-PPI-(NHCOC(2)H(4)PPh(2))(16) (5a) and DAB-PPI-(NHCOC(2)H(4)PPh(2))(32) (5b) were obtained from diaminobutane-poly(trimethyleneamine) dendrimers. The purification of products 5a,b was followed by GPC methods, and the compounds were identified by analytical and NMR spectroscopic data. Treatment of the diphenylphosphino-terminated compounds 2a,b and 5a,b with equivalent amounts of (dimethyl sulfide)gold(I) chloride afforded the corresponding mono-, di-, hexadeca-, and dotriacontanuclear gold(I) complexes 3a,b and 6a,b, respectively, with terminal (diphenylphosphine)gold(I) chloride groups (-PPh(2)AuCl) in good yields as stable colorless solids. Full coverage of all omega-phosphine functions was accomplished as confirmed again by NMR spectroscopy. For further delineation of the configuration of the peptide-phosphine spacer tentacles, X-ray structure analyses were performed for MeNHCOC(2)H(4)PPh(2)AuCl (3a, triclinic, space group P (1) over bar) and (CH2-NHCOC(2)H(4)PPh(2)AuCl)(2) (3b, monoclinic, space group C2/c). The conformation of the molecules and their packing can be rationalized on the basis of intermolecular NH...O hydrogen bonds, which in these cases exclude intra- and intermolecular Au-I...Au-I contacts.

  DOI：

  10.1021/ic950644l