2,6-dibromo-4,4-difluoro-8-(4-chlorophenyl)-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene | 1357004-05-7

• 英文名称: 2,6-dibromo-4,4-difluoro-8-(4-chlorophenyl)-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene
• 英文别名: 2,6-dibromo-8-(4-chlorophenyl)-4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene
• CAS: 1357004-05-7
• 化学式: C₁₉H₁₆BBr₂ClF₂N₂
• 分子量: 516.418
• InChiKey: PITPWYRHFNCKGQ-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  10-(4-氯苯基)-5,5-二氟-1,3,7,9-四甲基-5H-二吡咯并[1,2-C:2',1'-f][1,3,2]重氮硼林-4-鎓-5-硼 在 氧气 、 copper(ll) bromide 作用下， 以 乙腈 为溶剂， 反应 12.0h， 以83%的产率得到2,6-dibromo-4,4-difluoro-8-(4-chlorophenyl)-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene
  参考文献：
  名称：

  BODIPY衍生物与溴化铜的高效便捷溴化

  摘要：

  以溴化铜（II）为溴化试剂，在温和的反应下，开发了一种高效，简便的单，二溴化1,3,5,7-四甲基取代的BODIPY的方法，收率良好。单溴或二溴的选择性很大程度上取决于反应的添加剂。 铜-溴化-选择性-荧光染料- 4,4-二氟-4-硼-3a，4a-二氮杂-小号-indacenes

  DOI：

  10.1055/s-0031-1289637

文献信息

• Regioselective 2,6-dihalogenation of BODIPYs in 1,1,1,3,3,3-hexafluoro-2-propanol and preparation of novel meso-alkyl polymeric BODIPY dyes
  作者：Liang Wang、Jian-Wei Wang、Ai-jun Cui、Xiao-Xiao Cai、Yan Wan、Qun Chen、Ming-Yang He、Wei Zhang

  DOI：10.1039/c3ra41298a

  日期：——

  Regioselective 2,6-halogenation of BODIPYs in hexafluoro-2-propanol (HFIP) afforded products in less than 5 min. Halogenated BODIPYs were subjected to Pd-catalyzed cross-coupling reactions to form novel meso-alkyl polymeric BODIPY dyes.

  在六氟异丙醇（HFIP）中，对BODIPYs进行区域选择性的2,6-卤化反应，在不到5分钟内获得了产物。卤化的BODIPYs经过Pd催化的交叉偶联反应形成了新型的meso-烷基聚合物BODIPY染料。
• Facile and environmentally friendly halogenation of BODIPYs in deep eutectic solvent
  作者：Liang Wang、Kai-qiang Zhu、Qun Chen、Ming-yang He

  DOI：10.1016/j.dyepig.2014.07.024

  日期：2015.1

  A deep eutectic solvent based on choline chloride and 1,1,1,3,3,3-hexafluoro-2-propanol was prepared. This deep eutectic solvent was used as the reaction medium for halogenation of boron dipyrromethene in the presence of N-halosuccinimide, which delivered the corresponding products in good to excellent yields (79-94%) in short reaction time (usually within 30 min). Moreover, this deep eutectic solvent could be easily prepared, recovered and reused for several runs without significant loss in the yields. (C) 2014 Elsevier Ltd. All rights reserved.