| 1425319-46-5

• CAS: 1425319-46-5
• 化学式: C₃₄H₃₆Cl₂N₄Ru₂
• 分子量: 773.733
• InChiKey: GQEVVUZVZLLNPW-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  甲醇 、 、 silver trifluoromethanesulfonate 反应 2.0h， 生成
  参考文献：
  名称：

  Growth Inhibitory Activity of a Bis-Benzimidazole-Bridged Arene Ruthenium Metalla-Rectangle and -Prism

  摘要：

  Two new supramolecular coordination complexes (SCCs) were obtained from the self-assembly of a new bis-benzimidazole bridged Ru acceptor, 4, with dipyridyl and tripyridyl donors, respectively. As part of a growing library of anticancer-active Ru-based SCCs, metalla-prism 6 selectively showed high cytotoxicities relative to cisplatin for a series of cancer cell lines, with IC50 values as low as 8.41 mu M for MCF7 cells, as determined from MTS assays.

  DOI：

  10.1021/om301174s
• 作为产物：
  描述：

  [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂ 、 2-(1H-苯并咪唑-2-基)-1H-苯并咪唑 在 sodium acetate 作用下， 以 乙醇 为溶剂， 以72%的产率得到
  参考文献：
  名称：

  Growth Inhibitory Activity of a Bis-Benzimidazole-Bridged Arene Ruthenium Metalla-Rectangle and -Prism

  摘要：

  Two new supramolecular coordination complexes (SCCs) were obtained from the self-assembly of a new bis-benzimidazole bridged Ru acceptor, 4, with dipyridyl and tripyridyl donors, respectively. As part of a growing library of anticancer-active Ru-based SCCs, metalla-prism 6 selectively showed high cytotoxicities relative to cisplatin for a series of cancer cell lines, with IC50 values as low as 8.41 mu M for MCF7 cells, as determined from MTS assays.

  DOI：

  10.1021/om301174s

文献信息

• Molecular self-assembly of arene-Ru based interlocked catenane metalla-cages
  作者：Anurag Mishra、Abhishek Dubey、Jin Wook Min、Hyunuk Kim、Peter J. Stang、Ki-Whan Chi

  DOI：10.1039/c4cc01991a

  日期：——

  Two interlocked and two simple trigonal prisms are formed through the coordination self-assembly of arene-Ru acceptors with a new tridentate donor.

  通过芳香烃-Ru受体与一种新的三齿配体的协同自组装，形成了两个相互锁定的和两个简单的三角柱。