FcC2C(O)(p-EtPh) | 1198428-26-0

• 英文名称: FcC2C(O)(p-EtPh)
• CAS: 1198428-26-0
• 化学式: C₂₁H₁₈FeO
• 分子量: 342.22
• InChiKey: UZCCXMBZGZMJKV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为反应物：
  描述：

  1,3-二甲基-6-氨基脲嘧啶 、 FcC2C(O)(p-EtPh) 在 nickel (II) cyanide * n H2O CO 、 KCN 作用下， 以 sodium hydroxide 为溶剂， 以72%的产率得到1-p-ethylphenyl-3-methylamino-3-ferrocenyl-2-propenone
  参考文献：
  名称：

  Synthesis of ferrocenyl-β-enamino ketones: A search of ferrocenylpyrido[2,3-d]pyrimidines using a Ni(CN)2/NaOH/KCN system as catalytic precursor

  摘要：

  New ferrocenyl-beta-enamino ketones (1-6), were obtained from 6-amino-1,3-dimethyluracil and several ferrocenyl-alpha-ketoalkynes via MeNH- anion in a monophasic aqueous system containing Ni(CN)(2)/CO/NaOH/H2O/KCN are described. A mechanism for obtaining of beta-enamino ketones is suggested. (C) 2009 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2009.07.017

文献信息

• Synthesis of new 7-ferrocenyl-β-enaminone-coumarins and ferrocenyl-pyrano[3,2-g]quinolin-2-ones from coumarin and ferrocenyl-α-ketoalkynes using Ni(CN)2/NaOH/H2O/CO/KCN aqueous catalytic system
  作者：Ivonne Arellano、Pankaj Sharma、Laura Rubio-Perez、Armando Cabrera、Noé Rosas、A. Toscano

  DOI：10.1016/j.jorganchem.2011.11.010

  日期：2012.3

  New ferrocenyl-beta-enaminone-coumarins (1a-5a) and ferrocenyl-pyrano[3,2-g] quinolin-2-ones (1b-5b) were obtained through a heterocyclization reaction from 7-amino-4-methyl-2H-chromen-2-one and several ferrocenyl-alpha-ketoalkynes in a nickel homogeneous aqueous catalytic system formed by Ni(CN)(2)/CO/NaOH/KCN. In the absence of this catalytic system neither ferrocenyl substituted chromenone nor ferrocenyl-heterocycle was obtained. A possible mechanism is suggested for the synthesis of -beta-enaminone-coumarins and pyrano[3,2-g] quinolinones. Molecular structure of 7-(1-ferrocenyl-3-(4-bromophenyl)-3-oxoprop-1-enylamino)-4-methyl-2H-chromen-2-one (5a) has been determined. (C) 2011 Elsevier B. V. All rights reserved.