4-[(ferrocenylamino)methyl]thiophene-3-boronic acid | 1610432-88-6

• 英文名称: 4-[(ferrocenylamino)methyl]thiophene-3-boronic acid
• CAS: 1610432-88-6
• 化学式: C₁₅H₁₆BFeNO₂S
• 分子量: 341.022
• InChiKey: XRHPQDZEZGSXDH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  在 sodium tetrahydroborate 作用下， 以 乙醇 为溶剂， 反应 0.25h， 以93%的产率得到4-[(ferrocenylamino)methyl]thiophene-3-boronic acid
  参考文献：
  名称：

  Combining ferrocene, thiophene and a boronic acid: a hybrid ligand for reagentless electrochemical sensing of cis-diols

  摘要：

  A redox-active affinity ligand suitable for reagentless sensing of cis-diols was synthesised and characterised. 4-[(Ferrocenylamino)methyl]thiophene-3-boronic acid (FcTBA) was allowed to interact with the model cis-diol, sorbitol. A discrete, cathodic shift of the redox potential was observed upon interaction of FcTBA with sorbitol thus providing simultaneous differentiation between the free and bound forms of this sensor molecule. Similar behaviour was observed also for FcTBA co-immobilised with thiophene in a mixed self-assembled monolayer on a gold electrode. (C) 2014 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license

  DOI：

  10.1016/j.tetlet.2014.04.036