3-(pyridine-4-thione)-8-(4-methoxyphenyl)-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene | 1380598-89-9

• 英文名称: 3-(pyridine-4-thione)-8-(4-methoxyphenyl)-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene
• CAS: 1380598-89-9
• 化学式: C₂₁H₁₆BF₂N₃OS
• 分子量: 407.251
• InChiKey: MHMFHWIQPSYMOL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为反应物：
  描述：

  3-(pyridine-4-thione)-8-(4-methoxyphenyl)-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene 在 mercury(II) diacetate 、 水 作用下， 以 甲醇 、 氯仿 为溶剂， 生成 3-(pyridine-4-one)-8-(4-methoxyphenyl)-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene
  参考文献：
  名称：

  3-(Pyridine-4-thione)BODIPY as a chemodosimeter for detection of Hg(II) ions

  摘要：

  A new chemodosimeter for detection of Hg(II) ions based on boron-dipyrromethene (BODIPY) is developed. The 3-(pyridine-4-thione)BODIPY was synthesized in high yield by treating 3-(pyridine-4-one)BODIPY with Lawesson's reagent. The 3-(pyridine-4-thione) BODIPY was confirmed by HR-MS mass, H-1, H-1-H-1 COSY, F-19 and B-11 NMR techniques. In H-1 NMR, the protons which are adjacent to sulfur in 3-(pyridine-4-thione)BODIPY showed similar to 1 ppm downfield shift compared to equivalent protons in 3-(pyridine-4-one)BODIPY. The absorption and electrochemical properties experienced slight changes in 3-(pyridine-4-thione)BODIPY compared to 3-(pyridine-4-one)BODIPY. The compound 3-(pyridine-4-thione)BODIPY is very weakly fluorescent compared to 3-(pyridine-4-one)BODIPY. Furthermore, 3(pyridine-4-thione)BODIPY can be used as an exclusive chemodosimeter for Hg2+ ion as it shows significant enhancement in the fluorescence intensity and a dramatic visible color change from pink to fluorescent green in the presence of Hg(II) ions. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.dyepig.2012.03.015
• 作为产物：
  描述：

  3-(pyridine-4-one)-8-(4-methoxyphenyl)-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene 在 劳森试剂 作用下， 以 甲苯 为溶剂， 反应 2.0h， 以50%的产率得到3-(pyridine-4-thione)-8-(4-methoxyphenyl)-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene
  参考文献：
  名称：

  3-(Pyridine-4-thione)BODIPY as a chemodosimeter for detection of Hg(II) ions

  摘要：

  A new chemodosimeter for detection of Hg(II) ions based on boron-dipyrromethene (BODIPY) is developed. The 3-(pyridine-4-thione)BODIPY was synthesized in high yield by treating 3-(pyridine-4-one)BODIPY with Lawesson's reagent. The 3-(pyridine-4-thione) BODIPY was confirmed by HR-MS mass, H-1, H-1-H-1 COSY, F-19 and B-11 NMR techniques. In H-1 NMR, the protons which are adjacent to sulfur in 3-(pyridine-4-thione)BODIPY showed similar to 1 ppm downfield shift compared to equivalent protons in 3-(pyridine-4-one)BODIPY. The absorption and electrochemical properties experienced slight changes in 3-(pyridine-4-thione)BODIPY compared to 3-(pyridine-4-one)BODIPY. The compound 3-(pyridine-4-thione)BODIPY is very weakly fluorescent compared to 3-(pyridine-4-one)BODIPY. Furthermore, 3(pyridine-4-thione)BODIPY can be used as an exclusive chemodosimeter for Hg2+ ion as it shows significant enhancement in the fluorescence intensity and a dramatic visible color change from pink to fluorescent green in the presence of Hg(II) ions. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.dyepig.2012.03.015