| 898831-16-8

• CAS: 898831-16-8
• 化学式: C₄₄H₆₈Fe₂N
• 分子量: 722.725
• InChiKey: SSILWEYNMCREQP-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  bis(11-ferrocenylundecyl) dimethylammonium bromide 以 not given 为溶剂， 生成
  参考文献：
  名称：

  Ferrocene-Containing Cationic Lipids: Influence of Redox State on Cell Transfection

  摘要：

  A ferrocene-containing, redox-active cationic lipid that can be transformed using electrochemical methods yields large differences in cell transfection depending on the oxidation state of the lipid. Expression of enhanced green fluorescent protein and firefly luciferase occurs at very high levels when DNA lipoplexes are formulated using the lipid in the reduced state. In contrast, transfection is negligible when oxidized lipid is used. These observations suggest the basis of a general method that could be used to transform inactive lipoplex formulations to an active form through the application of externally applied electrical potentials. The ability to activate lipoplexes toward transfection electrochemically and "on demand" could create new opportunities to deliver DNA in vitro and in vivo with both spatial and temporal control.

  DOI：

  10.1021/ja054038t