cis-[Pt(II)(pyridinecarboxaldimine-3-C6H4CF3)Cl2] | 773859-95-3

• 英文名称: cis-[Pt(II)(pyridinecarboxaldimine-3-C6H4CF3)Cl2]
• CAS: 773859-95-3
• 化学式: C₁₃H₉Cl₂F₃N₂Pt
• 分子量: 516.209
• InChiKey: FVHRRHCMQOXPCN-XNWZNIMTSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  (3-(trifluoromethyl)phenyl)pyridine-2-ylmethylene-amine 、 [PtCl2(cis-cyclooctene)]2 以 二氯甲烷 为溶剂， 以65%的产率得到cis-[Pt(II)(pyridinecarboxaldimine-3-C6H4CF3)Cl2]
  参考文献：
  名称：

  Synthesis, characterization, and cytotoxicities of palladium(II) and platinum(II) complexes containing fluorinated pyridinecarboxaldimines

  摘要：

  Condensation of 2-pyridinecarboxaldehyde with several primary amines containing fluorine groups gave the corresponding pyridinecarboxaldimines (N-N'). Addition of these ligands to [MCl2(coe)](2) (M = Pd, Pt; coe = cis-cyclooctene) gave complexes of the type cis-MCl2(N-N') [Pd (3) Pt (4)] in moderate to high yields. All palladium and platinum complexes were examined for their potential cytotoxicities against OV2008 (human ovarian carcinoma) and the analogous cisplatin-resistant C13. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2004.06.013