4-[(5-甲基-2-呋喃基)甲基]-1H-咪唑 | 226571-19-3

• 中文名称: 4-[(5-甲基-2-呋喃基)甲基]-1H-咪唑
• 中文别名: 2-[4-[(2-氯-4-硝基苯基)偶氮]-4,5-二氢-3-甲基-5-羰基-1H-吡唑-1-基]乙基(3,4-dichlorophenyl)氨基甲酸酯
• 英文名称: 4(5)-(5-methylfuran-2-ylmethyl)-1H-imidazole
• 英文别名: 4-((5-Methylfuran-2-yl)methyl)-1H-imidazole；5-[(5-methylfuran-2-yl)methyl]-1H-imidazole
• CAS: 226571-19-3
• 化学式: C₉H₁₀N₂O
• 分子量: 162.191
• InChiKey: SUCABAJRVMXZLC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  41.8
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• ALPHA-2B RECEPTOR AGONIST AND 5HT4 SEROTONIN RECEPTOR COMPOSITIONS FOR TREATING GASTROINTESTINAL MOTILITY DISORDERS
  申请人：Brooks Gregory F.

  公开号：US20080153825A1

  公开（公告）日：2008-06-26

  Disclosed herein is a pharmaceutical composition comprising a 5-HT4 serotonin receptor agonist and an alpha-2B receptor agonist. The composition is effective for treating gastrointestinal motility disorders, and methods of treating such disorders using the composition and compounds comprising it are also disclosed.
• ALPHA-2B RECEPTOR AGONIST AND ANTICONVULSANT COMPOSITIONS FOR TREATING CHRONIC PAIN
  申请人：Gil Daniel W.

  公开号：US20080153874A1

  公开（公告）日：2008-06-26

  Disclosed herein is a pharmaceutical composition comprising a pain-relieving anticonvulsant and an alpha-2B receptor agonist. The composition is effective for treating chronic pain, and methods of treating chronic pain using the composition and the compounds comprising it are also disclosed.
• ALPHA-2B RECEPTOR AGONIST AND ACID REDUCER COMPOSITIONS FOR TREATING GASTROINTESTINAL MOTILITY DISORDERS
  申请人：Brooks Gregory F.

  公开号：US20080153881A1

  公开（公告）日：2008-06-26

  Disclosed herein is a pharmaceutical composition comprising an acid reducer and an alpha-2B receptor agonist. The composition is effective for treating gastrointestinal motility disorders, and methods of treating such disorders using the composition and compounds comprising it are also disclosed.
• ALPHA-2B RECEPTOR AGONIST AND RELAXANT COMPOSITIONS FOR TREATING GASTROINTESTINAL MOTILITY DISORDERS
  申请人：Brooks Gregory F.

  公开号：US20080153927A1

  公开（公告）日：2008-06-26

  Disclosed herein is a pharmaceutical composition comprising a relaxant and an alpha-2B receptor agonist. The composition is effective for treating gastrointestinal motility disorders, and methods of treating such disorders using the composition and compounds comprising it are also disclosed.
• ALPHA-2B ADRENERGIC RECEPTOR AGONIST AND SEROTONIN-NOREPINEPHRINE REUPTAKE INHIBITOR COMPOSITIONS FOR TREATING CHRONIC PAIN
  申请人：Gil Daniel W.

  公开号：US20100016355A1

  公开（公告）日：2010-01-21

  Disclosed herein is a pharmaceutical composition comprising a serotonin-norepinephrine reuptake inhibitor and an alpha-2B receptor agonist. The composition is effective for treating chronic pain, and methods of treating pain using the composition and compounds comprising it are also disclosed.