[(125)I]-2-iodo-p-carborane | 620536-26-7

• 英文名称: [(125)I]-2-iodo-p-carborane
• CAS: 620536-26-7
• 化学式: C₂H₁₁B₁₀I
• 分子量: 268.219
• InChiKey: VABRIGUFSWLCTO-QBRXFKMYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  sodium iodide 、 2-iodo-closo-1,12-dodecaborane 在 trans-di(μ-acetato)bis[o-(di-o-tolylphosphino)benzyl]dipalladium(II) 作用下， 以 甲苯 为溶剂， 生成 [(125)I]-2-iodo-p-carborane
  参考文献：
  名称：

  High yield [125I]iodide-labeling of iodinated carboranes by palladium-catalyzed isotopic exchange

  摘要：

  We have recently shown the feasibility of palladium-catalyzed isotopic exchange between [I-125]iodide and 2-iodo-para-carborane. In this work we have modified the methodology and extended its application to a wider range of iodinated carboranes. Thus, by using Herrmann's catalyst in toluene at 100 degreesC, 2-I-p-, 3-I-o-, 9-I-o-, 9-I-m-carborane, 1-phenyl-3-I-o-carborane and 1,2-diphenyl-3-I-o-carborane have been radiolabeled with (125)iodine in high to excellent yields. (C) 2003 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0022-328x(03)00344-9