| 197915-92-7

• CAS: 197915-92-7
• 化学式: C₂₄H₃₂FeN₂O₈
• 分子量: 532.374
• InChiKey: KQGMIUVZFBCRER-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  、 potassium hydroxide 以 甲醇 为溶剂， 以71%的产率得到
  参考文献：
  名称：

  1,2‐FDTA: A Ferrocene‐Based Redox‐Active EDTA Analogue with a High Ca ²⁺ /Mg ²⁺ and Ca ²⁺ /Sr ²⁺ Selectivity in Aqueous Solution

  摘要：

  Abstract1, 2‐Ferrocenemethylenediyldiamino tetraacetate (1,2‐FDTA) is a redox‐active relative of EDTA and was synthesized in the reaction of 1,2‐bis(chloromethyl)ferrocene with iminodiacetate methyl ester followed by cleavage of the ester with methanolic KOH. Potentiometric determination of the stability constants of the complexes of 1,2‐FDTA with the alkaline earth metal ions showed this ligand to display a higher Ca2+/Mg2+ and Ca2+/Sr2+ selectivity (Ca2+ log K = 6.56, Mg2+ log K = 4.65, Sr2+ log K = 3.32) than EDTA itself. The redox potential of 1,2‐FDTA‐Ca2+ determined in aqueous solution by cyclic voltammetry was found to be anodically shifted by +50 mV with respect to that of the calcium free complex. Consequently the redox‐inactive calcium can be determined electrochemically in aqueous solution with a high selectivity with respect to the other alkaline earth metal ions.

  DOI：

  10.1002/cber.19971301008
• 作为产物：
  描述：

  1,2-bis(chloromethyl)ferrocene 、 亚氨基二乙酸二甲酯 在 NEt₃ 作用下， 以 乙醚 为溶剂， 以44%的产率得到
  参考文献：
  名称：

  1,2‐FDTA: A Ferrocene‐Based Redox‐Active EDTA Analogue with a High Ca ²⁺ /Mg ²⁺ and Ca ²⁺ /Sr ²⁺ Selectivity in Aqueous Solution

  摘要：

  Abstract1, 2‐Ferrocenemethylenediyldiamino tetraacetate (1,2‐FDTA) is a redox‐active relative of EDTA and was synthesized in the reaction of 1,2‐bis(chloromethyl)ferrocene with iminodiacetate methyl ester followed by cleavage of the ester with methanolic KOH. Potentiometric determination of the stability constants of the complexes of 1,2‐FDTA with the alkaline earth metal ions showed this ligand to display a higher Ca2+/Mg2+ and Ca2+/Sr2+ selectivity (Ca2+ log K = 6.56, Mg2+ log K = 4.65, Sr2+ log K = 3.32) than EDTA itself. The redox potential of 1,2‐FDTA‐Ca2+ determined in aqueous solution by cyclic voltammetry was found to be anodically shifted by +50 mV with respect to that of the calcium free complex. Consequently the redox‐inactive calcium can be determined electrochemically in aqueous solution with a high selectivity with respect to the other alkaline earth metal ions.

  DOI：

  10.1002/cber.19971301008