[RuCl(4'-(3-benzyloxyphenyl)-2,2':6',2''-terpyridine)(2,9-dimethyl-1,10-phenanthroline)][ClP4] | 1261934-39-7

• 英文名称: [RuCl(4'-(3-benzyloxyphenyl)-2,2':6',2''-terpyridine)(2,9-dimethyl-1,10-phenanthroline)][ClP4]
• 英文别名: [RuCl(3-boptpy)(dmphen)][ClO4]
• CAS: 1261934-39-7
• 化学式: C₄₂H₃₃ClN₅ORu*ClO₄
• 分子量: 859.731
• InChiKey: XVWHYIPUUAUBJQ-UHFFFAOYSA-L

反应信息

• 作为产物：
  描述：

  新铜试剂 、 [RuCl3(4'-(3-benzyloxyphenyl)-2,2':6',2''-terpyridine)] 、 sodium perchlorate 在 LiCl 、 Et₃N 作用下， 以 乙醇 、 水 、 乙腈 为溶剂， 生成 [RuCl(4'-(3-benzyloxyphenyl)-2,2':6',2''-terpyridine)(2,9-dimethyl-1,10-phenanthroline)][ClP4]
  参考文献：
  名称：

  Antimicrobial and nuclease activity of mixed polypyridyl ruthenium(II) complexes

  摘要：

  The ruthenium(II) complexes with 2,9-dimethy1-1,10-phenanthroline (dmphen) and terpyridine derivatives have been synthesized and screened for their antimicrobial potency. The interaction of these complexes with Herring Sperm DNA was investigated by thermal denaturation, viscosity measurements, gel electrophoresis and spectrophotometric methods. The results indicate that the complexes bound to DNA via partial intercalative mode. The salt-dependent binding of these complexes has been determined by UV-Vis spectrophotometric titration. The contribution of the non-electrostatic binding free energy (Delta G(t)(o)) to the total binding free energy change (Delta G(o)) is found to be similar to 88% at [Na+] =0.075 M. The large value suggests that the stabilization of the DNA binding is mostly due to the contribution of non-electrostatic process. (C) 2010 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.inoche.2010.08.022