| 1266339-31-4

• CAS: 1266339-31-4
• 化学式: C₁₄H₁₆Cl₂CuN₂O₂
• 分子量: 378.745
• InChiKey: NGPLOAMIJJYGJE-QKEVMJATSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  copper(II) choride dihydrate 、 (S,S)-6,6'-bis-(1-hydroxyethyl)-2,2'-bipyridine 以 乙醇 、 二氯甲烷 为溶剂， 以42%的产率得到
  参考文献：
  名称：

  Chiral copper–bipyridine complexes: Synthesis, characterization and mechanistic studies on asymmetric cyclopropanation

  摘要：

  Chiral bipyridine ligands of different steric properties when reacted with CuCl(2) formed orange, yellow or green solids of new copper(II) complexes, [Cu(L)Cl(2)] (L = 12-6), in good yield. Together with Ku(L1)Cl(2)], these complexes were characterized in solution by UV-Vis spectroscopy and cyclic voltammetry. The complexes give d-d transitions between 860 and 970 nm, and exhibit one quasi-reversible Cu(II)/Cu(I) couple between +0.405 V and +0.516 V versus NHE. Two of the copper(II) complexes, [Cu(L5)Cl(2)] and [Cu(L6)Cl(2)], and a copper(I) complex of L1, [Cu(L1)01, were characterized by X-ray crystallography. The triflate derivatives of both the Cu(I) and Cu(II) complexes are active catalysts towards the cyclopropanation of ethyl diazoacetate with styrene. The asymmetric induction suffers when the size difference between the alkyl and alkoxyl groups was minimized. The mechanism of the cyclopropanation was studied with kinetic and competition experiments. The rate is first order in catalyst and ethyl diazoacetate, inverse order with styrene and is strongly affected by the counterion. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2010.10.021