difluorovanadium(IV)(2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy acetate) | 1080673-10-4

• 英文名称: difluorovanadium(IV)(2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy acetate)
• 英文别名: VF2(cetrizine(-H))2
• CAS: 1080673-10-4
• 化学式: C₄₂H₄₈Cl₂F₂N₄O₆V
• 分子量: 864.711
• InChiKey: KNWWWHBHHNXGSB-UHFFFAOYSA-J

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
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• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  四氟化钒 、 cetirizine dihydrochloride 以 甲醇 为溶剂， 以82%的产率得到difluorovanadium(IV)(2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy acetate)
  参考文献：
  名称：

  Difluorovanadium(IV) dicarboxylates: Coordination behavior and biological activity

  摘要：

  Different vanadium(IV) complexes of general formula VF2L2 have been synthesized, where L are various nonsteroidal antiinflammatory drugs. The complexes are characterized by elemental analysis, UV-visible, and infrared spectroscopy. The metal contents estimated by the ICP-AES method in the synthesized complexes are in good agreement with their calculated values and spectroscopic data proposed the octahedral geometry for the reported complexes. Conductance measurements show the nonelectrolytic nature of complexes. Biological screening tests against different bacteria and fungi show significant antibacterial and antifungal activity for all the complexes.

  DOI：

  10.1134/s1070328407080052